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Authors
Advisor(s)
Abstract(s)
RESUMO - Nas últimas décadas, ocorreu um número crescente de doenças fúngicas em animais
com etiologia constituída por fungos oportunistas e patogénicos. As infeções micóticas podem
ser classificadas, quanto ao local da lesão, em cutâneas, subcutâneas e sistémicas. Nas
infeções sistémicas, os agentes patogénicos fúngicos entram no hospedeiro através de uma
única via e disseminam-se para afetar vários sistemas do organismo. Nos gatos, as micoses
sistémicas são raras, porém são causa de morbidade e mortalidade significativas.
O objetivo deste estudo foi realizar a descrição das principais doenças fúngicas
sistémicas em gatos (criptococose, histoplasmose, blastomicose, coccidioidomicose e
esporotricose) e comparar a bibliografia com casos observados no Grupo Hospital do Gato.
São apresentados dois casos de gatos com diagnóstico de doença fúngica sistémica através
de exame físico, serológico, citológico, histopatológico, imagiológico e/ou molecular. Além de
um caso de criptococose felina, é apresentado um caso de histoplasmose felina importado do
Brasil, sendo esta a primeira descrição da doença em Portugal, visto que, durante a realização
desta dissertação não foram encontrados relatos de histoplasmose felina neste país.
Foi possível confirmar com esse estudo, que embora as doenças fúngicas sistémicas
sejam consideradas raras em gatos, sua ocorrência não deve ser esquecida numa lista de
diagnósticos diferenciais em casos de sinais clínicos com doença respiratória e/ou alterações
cutâneas, principalmente em pacientes que sejam oriundos de outros países, que tenham
historial de viagens. O diagnóstico das doenças pode ser difícil pois os sinais clínicos podem
ser inespecíficos e confundidos com patologias mais frequentemente observadas na rotina
clínica, além disso o diagnóstico pode depender da realização de múltiplos métodos
analíticos, podendo implicar em altos custos monetários ao tutor, o que pode ser um fator
limitante.
ABSTRACT - In recent decades, there has been an increasing number of fungal diseases in animals with an etiology consisting of opportunistic and pathogenic fungi. Mycotic infections can be classified, according to the location of the lesion, into cutaneous, subcutaneous and systemic. In systemic infections, fungal pathogens enter the host via a single pathway and spread to affect various body systems. In cats, systemic mycoses are rare, but they are a cause of significant morbidity and mortality. The aim of this study was to describe the main systemic fungal diseases in cats (cryptococcosis, histoplasmosis, blastomycosis, coccidioidomycosis and sporotrichosis) and to compare the bibliography with cases observed in Grupo Hospital do Gato. There are two cases of cats diagnosed with systemic fungal disease through physical, serological, cytological, histopathological, imaging and/or molecular examination. In addition to a case of feline cryptococcosis, a case of feline histoplasmosis imported from Brazil is presented, which is the first description of the disease in Portugal, as no reports of feline histoplasmosis were found in this country during the course of this dissertation It was possible to confirm with this study that, although systemic fungal diseases are considered rare in cats, their occurrence should not be forgotten in a list of differential diagnoses in cases of clinical signs with respiratory disease and/or skin changes, especially in patients who come from from other countries that have a history of travel. The diagnosis of diseases can be difficult because the clinical signs can be non-specific and confused with pathologies more frequently observed in clinical routine. Furthermore, the diagnosis may depend on the performance of multiple analytical methods, which may imply high monetary costs for the tutor, which can be a limiting factor.
ABSTRACT - In recent decades, there has been an increasing number of fungal diseases in animals with an etiology consisting of opportunistic and pathogenic fungi. Mycotic infections can be classified, according to the location of the lesion, into cutaneous, subcutaneous and systemic. In systemic infections, fungal pathogens enter the host via a single pathway and spread to affect various body systems. In cats, systemic mycoses are rare, but they are a cause of significant morbidity and mortality. The aim of this study was to describe the main systemic fungal diseases in cats (cryptococcosis, histoplasmosis, blastomycosis, coccidioidomycosis and sporotrichosis) and to compare the bibliography with cases observed in Grupo Hospital do Gato. There are two cases of cats diagnosed with systemic fungal disease through physical, serological, cytological, histopathological, imaging and/or molecular examination. In addition to a case of feline cryptococcosis, a case of feline histoplasmosis imported from Brazil is presented, which is the first description of the disease in Portugal, as no reports of feline histoplasmosis were found in this country during the course of this dissertation It was possible to confirm with this study that, although systemic fungal diseases are considered rare in cats, their occurrence should not be forgotten in a list of differential diagnoses in cases of clinical signs with respiratory disease and/or skin changes, especially in patients who come from from other countries that have a history of travel. The diagnosis of diseases can be difficult because the clinical signs can be non-specific and confused with pathologies more frequently observed in clinical routine. Furthermore, the diagnosis may depend on the performance of multiple analytical methods, which may imply high monetary costs for the tutor, which can be a limiting factor.
Description
Dissertação de Mestrado Integrado em Medicina Veterinária
Keywords
Gatos micoses criptococose histoplasmose Cats mycoses cryptococcosis histoplasmosis
Pedagogical Context
Citation
Silva MEV. 2021. Doenças fúngicas sistémicas em gatos : estudo de casos [dissertação de mestrado]. Lisboa: FMV-Universidade de Lisboa.
Publisher
Universidade de Lisboa, Faculdade de Medicina Veterinária