(1R,4S,5S)-5-((3-Hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-ol

Fortunato, Milene; Siopa, Filipa; Afonso, Carlos

http://hdl.handle.net/10451/47439

Utilize este identificador para referenciar este registo.

Nome:	Descrição:	Tamanho:	Formato:
molbank-2021-M1199-v2.pdf		1.14 MB	Adobe PDF	Ver/Abrir

Contacte-nos

Autores

Fortunato, Milene

Siopa, Filipa

Afonso, Carlos

Resumo(s)

Using environmentally friendly conditions, the nucleophilic ring-opening reaction of 6-azabicyclo[3.1.0]hex-3-en-2-ol with 1-methyl-1H-tetrazole-5-thiol provided a novel thiol-incorporated aminocyclopentitol, (1R,4S,5S)-5-((3-hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-ol, in excellent yield (95%). The newly synthesized compound was analyzed and characterized via 1H, 13C-NMR, HSQC, and mass spectral data.

Palavras-chave

Aminocyclopentitol Bicyclic aziridine Water chemistry Nucleophilic substitution

URI

http://hdl.handle.net/10451/47439

Citação

Fortunato M, Siopa F, Afonso C. (1R,4S,5S)-5-((3-Hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-ol. Molbank [Internet]. 2021 Apr 1;2021(2):M1199. Available from: http://dx.doi.org/10.3390/M1199