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(1R,4S,5S)-5-((3-Hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-ol

2021-04-01Journal article Open access
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dc.contributor.authorFortunato, Milene
dc.contributor.authorSiopa, Filipa
dc.contributor.authorAfonso, Carlos
dc.date.accessioned2021-04-15T10:56:35Z
dc.date.available2021-04-15T10:56:35Z
dc.date.issued2021-04-01
dc.description.abstractUsing environmentally friendly conditions, the nucleophilic ring-opening reaction of 6-azabicyclo[3.1.0]hex-3-en-2-ol with 1-methyl-1H-tetrazole-5-thiol provided a novel thiol-incorporated aminocyclopentitol, (1R,4S,5S)-5-((3-hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-ol, in excellent yield (95%). The newly synthesized compound was analyzed and characterized via 1H, 13C-NMR, HSQC, and mass spectral data.pt_PT
dc.description.sponsorshipThis research was funded by Fundação para a Ciência e a Tecnologia (FCT) (reference number: PTDC/QUI-QOR/32008/2017). The project leading to this application received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No. 951996.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFortunato M, Siopa F, Afonso C. (1R,4S,5S)-5-((3-Hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-ol. Molbank [Internet]. 2021 Apr 1;2021(2):M1199. Available from: http://dx.doi.org/10.3390/M1199pt_PT
dc.identifier.doi10.3390/M1199pt_PT
dc.identifier.urihttp://hdl.handle.net/10451/47439
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationStraightening training, research and innovation capacities in the valorization of bio-renewable resource
dc.relation.publisherversionhttps://www.mdpi.com/1422-8599/2021/2/M1199pt_PT
dc.subjectAminocyclopentitolpt_PT
dc.subjectBicyclic aziridinept_PT
dc.subjectWater chemistrypt_PT
dc.subjectNucleophilic substitutionpt_PT
dc.title(1R,4S,5S)-5-((3-Hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-olpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleStraightening training, research and innovation capacities in the valorization of bio-renewable resource
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FQUI-QOR%2F32008%2F2017/PT
oaire.awardURIinfo:eu-repo/grantAgreement/EC/H2020/951996/EU
oaire.citation.issue2pt_PT
oaire.citation.startPageM1199pt_PT
oaire.citation.titleMolbankpt_PT
oaire.citation.volume2021pt_PT
oaire.fundingStream9471 - RIDTI
oaire.fundingStreamH2020
person.familyNameGamito Fortunato
person.familyNameDeslgado Siopa
person.familyNameMateus Afonso
person.givenNameMilene Andreia
person.givenNameFilipa Alexandra
person.givenNameCarlos Alberto
person.identifier.ciencia-idAA16-A885-3ABD
person.identifier.ciencia-id6A16-150F-A9F9
person.identifier.ciencia-id6319-2E4C-5BE1
person.identifier.orcid0000-0003-1072-0709
person.identifier.orcid0000-0002-4514-9154
person.identifier.orcid0000-0002-7284-5948
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameEuropean Commission
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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