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Publication
The impact of COVID-19 on antimicrobial resistance
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Abstract(s)
Durante a pandemia, de 2020 a 2021, o consumo total de antibióticos de uso sistémico diminuiu. O presente trabalho visa investigar o impacto da pandemia de COVID-19 na resistência de antibióticos a Streptococcus pneumoniae (2010-2021), face às penicilinas e aos macrólidos, lincosamidas e estreptograminas, na Europa, através de uma análise de correlação de Spearman realizada. A redução na resistência a macrólidos foi associada ao menor consumo destes antibióticos, de forma estatisticamente significativa. Já para as penicilinas, por sua vez, esta correlação encontrada não é estatisticamente significativa. As intervenções nacionais para pacientes em ambulatório e hospitalizados, durante a pandemia de COVID-19, resultaram numa diminuição do uso de antibióticos, bem como na incidência e resistência de S. pneumoniae resistente (1).
During the pandemic, from 2020 to 2021, the total consumption of antibiotics for systemic use decreased. The present work aims to investigate the impact of the COVID-19 pandemic on antibiotic resistance of Streptococcus pneumoniae (2010-2021) to penicillins and macrolides, lincosamides and streptogramins in Europe. A Spearman correlation analysis was performed. A reduction in the resistance to macrolides was associated with the lower consumption of macrolides, lincosamides and streptogramins, with statistical significance. While for penicillins, the correlation could not be statistically confirmed. National interventions for ambulatory and hospitalized patients, during COVID-19 pandemic, resulted in a decrease in antibiotic usage, as well as incidence and resistance of resistant S. pneumoniae (1).
During the pandemic, from 2020 to 2021, the total consumption of antibiotics for systemic use decreased. The present work aims to investigate the impact of the COVID-19 pandemic on antibiotic resistance of Streptococcus pneumoniae (2010-2021) to penicillins and macrolides, lincosamides and streptogramins in Europe. A Spearman correlation analysis was performed. A reduction in the resistance to macrolides was associated with the lower consumption of macrolides, lincosamides and streptogramins, with statistical significance. While for penicillins, the correlation could not be statistically confirmed. National interventions for ambulatory and hospitalized patients, during COVID-19 pandemic, resulted in a decrease in antibiotic usage, as well as incidence and resistance of resistant S. pneumoniae (1).
Description
Trabalho Final de Mestrado Integrado, Ciências Farmacêuticas, 2023, Universidade de Lisboa, Faculdade de Farmácia.
Keywords
Antibiotic resistance Antimicrobial stewardship COVID-19 Medicines consumption Public health Mestrado Integrado - 2023