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Portugal é dos países europeus que apresenta maiores níveis de consumo de benzodiazepinas e fármacos análogos. De acordo com o relatório do International Narcotics Control Board esta classe farmacológica é das mais prescritas e usadas no mundo. Estes fármacos são muito úteis em várias situações clínicas, com principal indicação para o tratamento da ansiedade e insónia patológicas a curto prazo. Existe evidência clara de que o uso crónico destes medicamentos gera outcomes negativos e indesejáveis como a tolerância, dependência, síndrome de abstinência, quedas, fraturas ósseas, amnésia e disfunção cognitiva.
Os dados de monitorização de mercado do Infarmed e os dados estatísticos da Organização para a Cooperação e Desenvolvimento Económico evidenciam uma tendência de prescrição e consumo excessivo de benzodiazepinas e fármacos análogos em Portugal. Demonstram também uma prevalência significativa do uso crónico e inapropriado na população idosa. Em suma, sustentam um quadro preocupante, expõem um grave problema de Saúde Pública em Portugal, que necessita de um plano de intervenção bem estruturado. Os farmacêuticos, especialmente os comunitários, enquanto profissionais de saúde e agentes de Saúde Pública têm uma posição privilegiada para poder desempenhar um papel ativo no sentido de contrariar o consumo excessivo e promover o uso seguro e racional destes medicamentos. Futuramente, deverá ser desenvolvida maior investigação, direcionada para uma compreensão mais profunda deste problema multifatorial, como também para estudar o impacto da intervenção farmacêutica neste contexto.
Portugal is one of the European countries with the highest levels of consumption of benzodiazepines and similar drugs. According to the report of the International Narcotics Control Board, this pharmacological class is one of the most prescribed and used in the world. These drugs are very useful in various clinical situations, with the main indication for the treatment of pathological anxiety and insomnia in the short term. There is clear evidence that the chronic use of these drugs generates negative and undesirable outcomes such as tolerance, dependence, withdrawal syndrome, falls, bone fractures, amnesia and cognitive dysfunction. The market monitoring data from Infarmed and the statistical data from the Organization for Economic Cooperation and Development show a trend in prescription and excessive consumption of benzodiazepines and similar drugs in Portugal. They also demonstrate a significant prevalence of chronic and inappropriate use in the elderly population. In short, they support a worrying situation, expose a serious public health problem in Portugal, which needs a well-structured intervention plan. Pharmacists, especially community pharmacists, as health professionals and public health agents are in a privileged position to be able to play an active role in countering excessive consumption and promoting the safe and rational use of these medicines. In the future, more research should be developed, aimed at a deeper understanding of this multifactorial problem, as well as to study the impact of pharmaceutical intervention in this context.
Portugal is one of the European countries with the highest levels of consumption of benzodiazepines and similar drugs. According to the report of the International Narcotics Control Board, this pharmacological class is one of the most prescribed and used in the world. These drugs are very useful in various clinical situations, with the main indication for the treatment of pathological anxiety and insomnia in the short term. There is clear evidence that the chronic use of these drugs generates negative and undesirable outcomes such as tolerance, dependence, withdrawal syndrome, falls, bone fractures, amnesia and cognitive dysfunction. The market monitoring data from Infarmed and the statistical data from the Organization for Economic Cooperation and Development show a trend in prescription and excessive consumption of benzodiazepines and similar drugs in Portugal. They also demonstrate a significant prevalence of chronic and inappropriate use in the elderly population. In short, they support a worrying situation, expose a serious public health problem in Portugal, which needs a well-structured intervention plan. Pharmacists, especially community pharmacists, as health professionals and public health agents are in a privileged position to be able to play an active role in countering excessive consumption and promoting the safe and rational use of these medicines. In the future, more research should be developed, aimed at a deeper understanding of this multifactorial problem, as well as to study the impact of pharmaceutical intervention in this context.
Descrição
Trabalho Final de Mestrado Integrado, Ciências Farmacêuticas, 2020, Universidade de Lisboa, Faculdade de Farmácia.
Palavras-chave
Benzodiazepinas Consumo Farmacêutico Saúde pública Dependência Mestrado integrado - 2020
