Publicação
Contribution of FoxP3+ Tfr cells to overall human blood CXCR5+ T cells
| dc.contributor.author | Fonseca, Valter R | |
| dc.contributor.author | Graca, Luis | |
| dc.date.accessioned | 2022-08-25T14:37:26Z | |
| dc.date.available | 2022-08-25T14:37:26Z | |
| dc.date.issued | 2019 | |
| dc.description | © 2019 British Society for Immunology. This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) | pt_PT |
| dc.description.abstract | The identification that T follicular helper (Tfh) cells is critical for the emergence of germinal centre responses prompted the study of CXCR5-expressing CD4+ T cell subsets in autoimmunity. However, circulating CXCR5-expressing T cells are heterogeneous by containing Forkhead box protein 3 (FoxP3)+ T follicular regulatory (Tfr) cells in addition to bona fide Tfh cells. Such heterogeneity may hamper the analysis of the contribution of specific follicular T cell subsets for autoimmune pathogenesis. Therefore, separate assessment of Tfh and Tfr populations offer greater opportunities for stratification of autoimmune patients, such as Sjögren's syndrome patients. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Clin Exp Immunol. 2019 Mar;195(3):302-304 | pt_PT |
| dc.identifier.doi | 10.1111/cei.13245 | pt_PT |
| dc.identifier.eissn | 1365-2249 | |
| dc.identifier.issn | 0009-9104 | |
| dc.identifier.uri | http://hdl.handle.net/10451/54196 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Oxford University Press | pt_PT |
| dc.relation.publisherversion | https://academic.oup.com/cei | pt_PT |
| dc.subject | Foxp3 | pt_PT |
| dc.subject | Sjögren’s syndrome | pt_PT |
| dc.subject | T follicular helper cells | pt_PT |
| dc.subject | T follicular regulatory cells | pt_PT |
| dc.title | Contribution of FoxP3+ Tfr cells to overall human blood CXCR5+ T cells | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 304 | pt_PT |
| oaire.citation.issue | 3 | pt_PT |
| oaire.citation.startPage | 302 | pt_PT |
| oaire.citation.title | Clinical and Experimental Immunology | pt_PT |
| oaire.citation.volume | 195 | pt_PT |
| person.familyName | Fonseca | |
| person.familyName | Silva Graca | |
| person.givenName | Valter | |
| person.givenName | Luis Ricardo | |
| person.identifier | B-8887-2008 | |
| person.identifier.ciencia-id | 1B1F-BD57-821A | |
| person.identifier.ciencia-id | 6C19-B162-F561 | |
| person.identifier.orcid | 0000-0001-6707-8011 | |
| person.identifier.orcid | 0000-0001-6935-8500 | |
| person.identifier.scopus-author-id | 36138488700 | |
| rcaap.rights | restrictedAccess | pt_PT |
| rcaap.type | article | pt_PT |
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