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Advisor(s)
Abstract(s)
This study describes for the first time the iron- and copper-mediated gelation of FucoPol, fucoserich
bacterial polysaccharide. The ability of FucoPol to gel in the presence of metal cations, including
iron(III) and copper(II), was used for the preparation of hydrogel beads. Iron mediated the
formation of stable and not cytotoxic gel beads, while copper resulted in fragile and cytotoxic
ones. Copper-mediated beads coated with an iron-mediated gel layer were more stable and had
reduced cytotoxicity. The resulting polymeric structures had differing morphology, physical properties
and cytotoxicity, which support their use in several applications, including biomedicine, agriculture
and bioremediation
Description
Keywords
FucoPol hydrogel beads cytotoxicity
Pedagogical Context
Citation
Fialho L, Araújo D, Alves VD, Roma-Rodrigues C, Baptista PV, Fernandes AR, Freitas F, Reis MAM (2021). Cation-mediated gelation of the fucose-rich polysaccharide FucoPol: preparation and characterization of hydrogel beads and their cytotoxicity assessment. International Journal of Polymeric Materials and Polymeric Biomaterials, 70(2):90-99
Publisher
Taylor & Francis