Repository logo
 
Publication

Cation-mediated gelation of the fucose-rich polysaccharide FucoPol: preparation and characterization of hydrogel beads and their cytotoxicity assessment

2021Journal article Open access
Simple item page
dc.contributor.authorFialho, Letícia
dc.contributor.authorAraújo, Diana
dc.contributor.authorDelgado Alves, Vitor
dc.contributor.authorRoma-Rodrigues, Catarina
dc.contributor.authorBaptista, Pedro V.
dc.contributor.authorFernandes, Alexandra R.
dc.contributor.authorFreitas, Filomena
dc.contributor.authorReis, Maria A.M.
dc.date.accessioned2022-03-15T10:04:41Z
dc.date.available2023-01-01T01:30:24Z
dc.date.issued2021
dc.description.abstractThis study describes for the first time the iron- and copper-mediated gelation of FucoPol, fucoserich bacterial polysaccharide. The ability of FucoPol to gel in the presence of metal cations, including iron(III) and copper(II), was used for the preparation of hydrogel beads. Iron mediated the formation of stable and not cytotoxic gel beads, while copper resulted in fragile and cytotoxic ones. Copper-mediated beads coated with an iron-mediated gel layer were more stable and had reduced cytotoxicity. The resulting polymeric structures had differing morphology, physical properties and cytotoxicity, which support their use in several applications, including biomedicine, agriculture and bioremediationpt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFialho L, Araújo D, Alves VD, Roma-Rodrigues C, Baptista PV, Fernandes AR, Freitas F, Reis MAM (2021). Cation-mediated gelation of the fucose-rich polysaccharide FucoPol: preparation and characterization of hydrogel beads and their cytotoxicity assessment. International Journal of Polymeric Materials and Polymeric Biomaterials, 70(2):90-99pt_PT
dc.identifier.doihttps://doi.org/10.1080/00914037.2019.1695205pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.5/23783
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherTaylor & Francispt_PT
dc.relationApplied Molecular Biosciences Unit
dc.subjectFucoPolpt_PT
dc.subjecthydrogel beadspt_PT
dc.subjectcytotoxicitypt_PT
dc.titleCation-mediated gelation of the fucose-rich polysaccharide FucoPol: preparation and characterization of hydrogel beads and their cytotoxicity assessmentpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleApplied Molecular Biosciences Unit
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FMulti%2F04378%2F2019/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/PEst-OE%2FAGR%2FUI0245%2F2014/PT
oaire.citation.titleINTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALSpt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream5876
person.familyNameDelgado Alves
person.givenNameVitor
person.identifier1916677
person.identifier.ciencia-id2E1E-6918-4DB3
person.identifier.orcid0000-0002-4117-5582
person.identifier.scopus-author-id24536716000
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication8d1a8489-8789-4569-89e2-0bade23dd945
relation.isAuthorOfPublication.latestForDiscovery8d1a8489-8789-4569-89e2-0bade23dd945
relation.isProjectOfPublication8325b928-9908-40e3-b06a-c4cd3d6adede
relation.isProjectOfPublication8b6fdd6d-afeb-4879-acc8-08f447db384b
relation.isProjectOfPublication.latestForDiscovery8325b928-9908-40e3-b06a-c4cd3d6adede

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Fialho et al 2021.pdf
Size:
3.18 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

ISA - Artigos em Revistas Internacionais