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The bile acid tauroursodeoxycholic acid modulates phosphorylation and translocation of bad via phosphatidylinositol 3-kinase in glutamate-induced apoptosis of rat cortical neurons

dc.contributor.authorCastro, RE
dc.contributor.authorSola, S
dc.contributor.authorRamalho, RM
dc.contributor.authorSteer, CJ
dc.contributor.authorRodrigues, CMP
dc.date.accessioned2015-12-30T10:17:27Z
dc.date.available2015-12-30T10:17:27Z
dc.date.issued2004
dc.description.abstractNeurotoxicity associated with increased glutamate release results in cell death through both necrotic and apoptotic processes. In addition, tauroursodeoxycholic acid ( TUDCA), an endogenous bile acid, is a strong modulator of apoptosis in several cell typ
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dc.identifier.citationJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. - Vol. 311, n. 2 (NOV 2004), p. 845-852
dc.identifier.doihttp://dx.doi.org/10.1124/jpet.104.070532
dc.identifier.issn0022-3565
dc.identifier.urihttp://hdl.handle.net/10451/21073
dc.language.isoeng
dc.publisherAMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS
dc.subjectPharmacology & Pharmacy
dc.titleThe bile acid tauroursodeoxycholic acid modulates phosphorylation and translocation of bad via phosphatidylinositol 3-kinase in glutamate-induced apoptosis of rat cortical neurons
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage852por
oaire.citation.startPage845por
oaire.citation.titleJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICSpor
oaire.citation.volumeVol. 311por
rcaap.rightsrestrictedAccess
rcaap.typearticle

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