The bile acid tauroursodeoxycholic acid modulates phosphorylation and translocation of bad via phosphatidylinositol 3-kinase in glutamate-induced apoptosis of rat cortical neurons

Castro, RE; Sola, S; Ramalho, RM; Steer, CJ; Rodrigues, CMP

http://hdl.handle.net/10451/21073

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Neurotoxicity associated with increased glutamate release results in cell death through both necrotic and apoptotic processes. In addition, tauroursodeoxycholic acid ( TUDCA), an endogenous bile acid, is a strong modulator of apoptosis in several cell typ

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Pharmacology & Pharmacy

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http://hdl.handle.net/10451/21073

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JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. - Vol. 311, n. 2 (NOV 2004), p. 845-852

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AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS

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http://dx.doi.org/10.1124/jpet.104.070532

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FF - Produção Científica 2000-2009

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The bile acid tauroursodeoxycholic acid modulates phosphorylation and translocation of bad via phosphatidylinositol 3-kinase in glutamate-induced apoptosis of rat cortical neurons

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