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Cyclodextrins in cosmetics

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Resumo(s)

Cyclodextrins (CDs) are cyclic oligosaccharides obtained from the starch.(1, 2) The natural CDs are composed by six, seven or eight glucopyranose units, respectively, with a lipophilic central cavity.(2-7) The CDs most important property is their ability to form inclusion and non-inclusion complexes with a wide range of solid, liquid and gaseous compounds.(3, 8) This molecular complexation provides beneficial modifications for the guest molecules which cannot be achieved otherwise. The most important are solubility enhancement of highly insoluble guests, stabilization against the degradative effects of oxidation and control of the volatility and unpleasant odors.(3) Therefore, CDs are used in pharmaceutical(9), food(10), chemical(11), agricultural(12) and cosmetic(13) industry. A lot of studies have been made about the use of CDs in cosmetic preparations.(14) Procter & Gamble is one of the most important companies that invest in this revolutionary molecule.(8) They publish a lot of patents for many applications, such as skin creams(15), deodorants(16) and toothpastes(17). The skin care became a priority and brands like CoverGirl(18) and Olay(19) are good examples. Keywords:

Descrição

Trabalho Final de Mestrado Integrado, Ciências Farmacêuticas, Universidade de Lisboa, Faculdade de Farmácia, 2015

Palavras-chave

Cosmetics Cyclodextrins Inclusion complex Mestrado Integrado - 2015 Skin care

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