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Associação da doença renal crónica com a mortalidade global e cardiovascular
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A doença renal crónica é definida como a diminuição da função renal ou presença de lesão renal por um período de pelo menos três meses. É uma patologia que assume importância pela sua crescente prevalência, estimada em 9.1% na população mundial. A morbilidade e mortalidade associada a esta doença são muito elevadas. Apesar da melhoria dos cuidados prestados aos doentes renais crónicos, a sua mortalidade é superior à restante população, tendo sido a 12ª principal causa de morte na população mundial. A mortalidade deve-se não só à perda de função renal em si mas também a todas as alterações fisiopatológicas decorrentes da doença. Neste sentido, a mortalidade cardiovascular tem particular importância nestes doentes, reconhecendose como a principal causa de morte no doente com doença renal crónica. Sendo vários os fatores que se associam à elevada mortalidade cardiovascular na doença renal, o seu reconhecimento e valorização precoces é fundamental, de modo a que possam ser alvo de intervenção, numa tentativa de melhorar o prognóstico do doente. Na plataforma PubMed foram pesquisados os termos MeSH “Renal Insufficiency, Chronic”, “mortality” e "Cardiovascular Diseases/mortality". Foram selecionados os artigos escritos em inglês ou português, acerca da população humana, excluindo-se os que se referiam a ensaios em população não humana e pediátrica.
Chronic Kidney Disease is defined as a decrease in kidney function or presence of kidney injury for at least three months. It is a pathology that assumes particular importance due to its increasing prevalence, estimated in 9.1% in the world population. The morbidity and mortality associated with this disease are very high. Despite the improvement in the care provided to patients with chronic kidney disease, their mortality is higher than the general population, ranking as the 12th cause of death in the world population. The mortality is caused not only by the loss of kidney function itself but also by the physiopathology changes of the disease. Thus, the cardiovascular mortality has particular importance in this group of patients, being recognized as the main cause of death in people with chronic kidney disease. There are many factors associated with the high cardiovascular mortality in chronic kidney disease and early recognition is fundamental to intervene, in an attempt to improve the patient’s prognosis. It was researched in PubMed platform the MeSh terms “Renal Insufficiency, Chronic”, “mortality” and "Cardiovascular Diseases/mortality". Articles written in English or Portuguese about the human population were selected, excluding articles about nonhuman and pediatric population.
Chronic Kidney Disease is defined as a decrease in kidney function or presence of kidney injury for at least three months. It is a pathology that assumes particular importance due to its increasing prevalence, estimated in 9.1% in the world population. The morbidity and mortality associated with this disease are very high. Despite the improvement in the care provided to patients with chronic kidney disease, their mortality is higher than the general population, ranking as the 12th cause of death in the world population. The mortality is caused not only by the loss of kidney function itself but also by the physiopathology changes of the disease. Thus, the cardiovascular mortality has particular importance in this group of patients, being recognized as the main cause of death in people with chronic kidney disease. There are many factors associated with the high cardiovascular mortality in chronic kidney disease and early recognition is fundamental to intervene, in an attempt to improve the patient’s prognosis. It was researched in PubMed platform the MeSh terms “Renal Insufficiency, Chronic”, “mortality” and "Cardiovascular Diseases/mortality". Articles written in English or Portuguese about the human population were selected, excluding articles about nonhuman and pediatric population.
Descrição
Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2021
Palavras-chave
Doença renal crónica Mortalidade global Mortalidade cardiovascular Nefrologia