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Impact of heat stress on bovine sperm quality and competence
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Orientador(es)
Resumo(s)
Global warming has negatively influenced animal production performance, in addition to
animal well-being and welfare, consequently impairing the economic sustainability of the livestock
industry. Heat stress impact on male fertility is complex and multifactorial, with the fertilizing
ability of spermatozoa affected by several pathways. Among the most significative changes are the
increase in and accumulation of reactive oxygen species (ROS) causing lipid peroxidation and motility
impairment. The exposure of DNA during the cell division of spermatogenesis makes it vulnerable
to both ROS and apoptotic enzymes, while the subsequent post-meiotic DNA condensation makes
restoration impossible, harming later embryonic development. Mitochondria are also susceptible to
the loss of membrane potential and electron leakage during oxidative phosphorylation, lowering their
energy production capacity under heat stress. Although cells are equipped with defense mechanisms
against heat stress, heat insults that are too intense lead to cell death. Heat shock proteins (HSP)
belong to a thermostable and stress-induced protein family, which eliminate protein clusters and
are essential to proteostasis under heat stress. This review focuses on effects of heat stress on sperm
quality and on the mechanisms leading to defective sperm under heat stress.
Descrição
Áreas de pesquisa: Agriculture ; Veterinary Sciences ; Zoology - REVIEW
Palavras-chave
Heat stress Bovine Spermatozoa Spermatogenesis Fertility
Contexto Educativo
Citação
Capela L, Leites I, Romão R, Lopes-da-Costa L, Pereira RMLN. 2022. Impact of heat stress on bovine sperm quality and competence. Animals, 12(8):975. Doi: https://doi.org/10.3390/ ani12080975
Editora
MDPI