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Probing the microbiome to predict response to biologic therapy in Inflammatory Bowel Disease: one step closer to precision medicine?

dc.contributor.authorRevés, Joana
dc.contributor.authorChapman, Thomas P.
dc.contributor.authorSatsangi, Jack
dc.contributor.authorTorres, Joana
dc.date.accessioned2022-05-20T13:30:29Z
dc.date.available2022-05-20T13:30:29Z
dc.date.issued2022
dc.description© 2022 by the AGA Institutept_PT
dc.description.abstractCurrent treatment algorithms in inflammatory bowel disease (IBD) rely on a “trial and error” approach, and therefore, patients may receive ineffective and costly therapy for many months, with associated risks. Furthermore, after failure of the first biologic, response rates to second-line therapies drop considerably. Personalized medicine, which seeks to identify biomarkers that predict disease course and treatment efficacy, thus remains a significant unmet need in IBD.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationGastroenterology. 2022 Jun;162(7):2120-2122pt_PT
dc.identifier.doi10.1053/j.gastro.2022.03.028pt_PT
dc.identifier.eissn1528-0012
dc.identifier.issn0016-5085
dc.identifier.urihttp://hdl.handle.net/10451/53100
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/journal/gastroenterologypt_PT
dc.titleProbing the microbiome to predict response to biologic therapy in Inflammatory Bowel Disease: one step closer to precision medicine?pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage2122pt_PT
oaire.citation.issue7pt_PT
oaire.citation.startPage2120pt_PT
oaire.citation.titleGastroenterologypt_PT
oaire.citation.volume162pt_PT
person.familyNameTorres
person.givenNameJoana
person.identifier.orcid0000-0003-2895-5821
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication38a18ac5-f4d2-4748-adf8-d41eefac84ab
relation.isAuthorOfPublication.latestForDiscovery38a18ac5-f4d2-4748-adf8-d41eefac84ab

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