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Probing the microbiome to predict response to biologic therapy in Inflammatory Bowel Disease: one step closer to precision medicine?

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Resumo(s)

Current treatment algorithms in inflammatory bowel disease (IBD) rely on a “trial and error” approach, and therefore, patients may receive ineffective and costly therapy for many months, with associated risks. Furthermore, after failure of the first biologic, response rates to second-line therapies drop considerably. Personalized medicine, which seeks to identify biomarkers that predict disease course and treatment efficacy, thus remains a significant unmet need in IBD.

Descrição

© 2022 by the AGA Institute

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Contexto Educativo

Citação

Gastroenterology. 2022 Jun;162(7):2120-2122

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Fascículo

Editora

Elsevier

Licença CC

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