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Phosphorylation of a novel SOCS-box regulates assembly of the HIV-1 Vif-Cul5 complex that promotes APOBEC3G degradation

dc.contributor.authorMehle, A
dc.contributor.authorGoncalves, J
dc.contributor.authorSanta-Marta, M
dc.contributor.authorMcPike, M
dc.contributor.authorGabuzda, D
dc.date.accessioned2015-12-30T10:18:27Z
dc.date.available2015-12-30T10:18:27Z
dc.date.issued2004
dc.description.abstractHIV-1 Vif (viral infectivity factor) protein overcomes the antiviral activity of the DNA deaminase APOBEC3G by targeting it for proteasomal degradation. We report here that Vif targets APOBEC3G for degradation by forming an SCF-like E3 ubiquitin ligase co
dc.formatapplication/pdf
dc.identifier.citationGENES & DEVELOPMENT. - Vol. 18, n. 23 (DEC 1 2004), p. 2861-2866
dc.identifier.doihttp://dx.doi.org/10.1101/gad.1249904
dc.identifier.issn0890-9369
dc.identifier.urihttp://hdl.handle.net/10451/21601
dc.language.isoeng
dc.publisherCOLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
dc.subjectCell Biology
dc.subjectDevelopmental Biology
dc.subjectGenetics & Heredity
dc.titlePhosphorylation of a novel SOCS-box regulates assembly of the HIV-1 Vif-Cul5 complex that promotes APOBEC3G degradation
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage2866por
oaire.citation.startPage2861por
oaire.citation.titleGENES & DEVELOPMENTpor
oaire.citation.volumeVol. 18por
rcaap.rightsrestrictedAccess
rcaap.typearticle

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