Repository logo
 
No Thumbnail Available
Publication

Phosphorylation of a novel SOCS-box regulates assembly of the HIV-1 Vif-Cul5 complex that promotes APOBEC3G degradation

Use this identifier to reference this record.

Advisor(s)

Abstract(s)

HIV-1 Vif (viral infectivity factor) protein overcomes the antiviral activity of the DNA deaminase APOBEC3G by targeting it for proteasomal degradation. We report here that Vif targets APOBEC3G for degradation by forming an SCF-like E3 ubiquitin ligase co

Description

Keywords

Cell Biology Developmental Biology Genetics & Heredity

Pedagogical Context

Citation

GENES & DEVELOPMENT. - Vol. 18, n. 23 (DEC 1 2004), p. 2861-2866

Research Projects

Organizational Units

Journal Issue

Publisher

COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT

CC License

Altmetrics