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The clinical spectrum of response to narrowband‐UVB therapy in chronic plaque psoriasis: the lower limbs are the most difficult‐to‐treat body region

dc.contributor.authorBrazão, Cláudia
dc.contributor.authorAlpalhão, Miguel
dc.contributor.authorFilipe, Paulo
dc.date.accessioned2023-10-19T11:29:44Z
dc.date.available2023-10-19T11:29:44Z
dc.date.issued2023
dc.description© John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.pt_PT
dc.description.abstractPsoriasis is a common chronic inflammatory disorder with serious quality of life impairment. Psoriasis Area Severity Index (PASI) and Dermatology Life Quality Index (DLQI) are the most validated scores for accessing psoriasis severity and response to therapy. Plaque psoriasis is the most common form of the disease. In 20% of patients, it is moderate to severe and dictates the need for alternative therapeutic options (ultraviolet (UV) radiation therapy, systemic, or biologic therapy). According to the American Academy of Dermatology and National Psoriasis Foundation guidelines, phototherapy serves as a first-line safe and effective treatment for moderate to severe plaque psoriasis, as monotherapy or combination therapy, for patients requiring more than topical medications and/or those who have contraindications for systemic medications. The two major types of UV-therapy in psoriasis include photochemotherapy (UVAradiation plus psoralen) and narrowband UVB phototherapy (NBUVB) (UVB-radiation without photosensitizers). Both are effective therapies, but the latter has fewer risks. Though phototherapy is widely used, the literature still lacks evidence regarding the response range of plaque psoriasis, including the distinct clinical response of body segments.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPhotodermatol Photoimmunol Photomed. 2023 Sep;39(5):529-531pt_PT
dc.identifier.doi10.1111/phpp.12877pt_PT
dc.identifier.eissn1600-0781
dc.identifier.issn0905-4383
dc.identifier.urihttp://hdl.handle.net/10451/59899
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWileypt_PT
dc.relation.publisherversionhttps://onlinelibrary.wiley.com/journal/16000781pt_PT
dc.subjectPhototherapypt_PT
dc.subjectPsoriasispt_PT
dc.subjectUltraviolet Radiationpt_PT
dc.titleThe clinical spectrum of response to narrowband‐UVB therapy in chronic plaque psoriasis: the lower limbs are the most difficult‐to‐treat body regionpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage531pt_PT
oaire.citation.issue5pt_PT
oaire.citation.startPage529pt_PT
oaire.citation.titlePhotodermatology, Photoimmunology & Photomedicinept_PT
oaire.citation.volume39pt_PT
person.familyNameBrazão
person.familyNameBotas Alpalhão
person.familyNameFilipe
person.givenNameCláudia
person.givenNameMiguel Duarte
person.givenNamePaulo
person.identifier.ciencia-id121D-3A5D-E15C
person.identifier.ciencia-id171A-309C-C397
person.identifier.orcid0000-0002-4485-7124
person.identifier.orcid0000-0001-7672-0395
person.identifier.orcid0000-0002-7337-6493
person.identifier.scopus-author-id7003448874
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationf6d53aae-12c4-4351-b802-156ad5c54c46
relation.isAuthorOfPublicationfb900519-fed0-4da7-a343-22bd2ef7ba3c
relation.isAuthorOfPublicationac4119d7-4c3c-471a-9723-f8b8e7543f55
relation.isAuthorOfPublication.latestForDiscoveryac4119d7-4c3c-471a-9723-f8b8e7543f55

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