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Cytokines and angiogenesis in the corpus luteum

dc.contributor.authorGalvão, António M.
dc.contributor.authorFerreira-Dias, Graça
dc.contributor.authorSkarzynski, Dariusz J.
dc.date.accessioned2014-09-22T14:31:02Z
dc.date.available2014-09-22T14:31:02Z
dc.date.issued2013
dc.descriptionArticles in International Journalspor
dc.description.abstractIn adults, physiological angiogenesis is a rare event, with few exceptions as the vasculogenesis needed for tissue growth and function in female reproductive organs. Particularly in the corpus luteum(CL), regulation of angiogenic process seems to be tightly controlled by opposite actions resultant fromthe balance between pro- and antiangiogenic factors. It is the extremely rapid sequence of events that determines the dramatic changes on vascular and nonvascular structures, qualifying the CL as a great model for angiogenesis studies. Using the mare CL as a model, reports on locally produced cytokines, such as tumor necrosis factor α (TNF), interferon gamma (IFNG), or Fas ligand (FASL), pointed out their role on angiogenic activity modulation throughout the luteal phase.Thus, the main purpose of this review is to highlight the interaction between immune, endothelial, and luteal steroidogenic cells, regarding vascular dynamics/changes during establishment and regression of the equine CL.por
dc.identifier.citationGalvão, A.M., Ferreira-Dias, G.M., & Skarzynski, D.J. (2013). Cytokines and angiogenesis in the corpus luteum. Mediators of Inflammation 2013(Article ID 420186), 1-11. doi: 10.1155/2013/420186por
dc.identifier.doi10.1155/2013/420186
dc.identifier.issn0962-9351
dc.identifier.urihttp://hdl.handle.net/10400.5/7197
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherHindawi Publishing Corporation. Academic Editor Jeffrey H. Ruthpor
dc.relation.publisherversionhttp://www.hindawi.com/journals/mi/2013/420186/por
dc.subjectCytokinepor
dc.subjectCorpus luteumpor
dc.subjectAngiogenesispor
dc.titleCytokines and angiogenesis in the corpus luteumpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage11por
oaire.citation.startPage1por
oaire.citation.titleMediators of Inflammationpor
oaire.citation.volume2013, Article ID 420186por
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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