Orientador(es)
Resumo(s)
A emergência de resistência aos fármacos usados no tratamento da tuberculose e, em particular, da tuberculose multirresistente (TBMR), tem revelado ser uma grande ameaça à efectividade do seu controlo. Em Portugal, a proporção de casos incidentes de TBMR situa-se dentro da mediana dos países da Europa Ocidental, constituindo aproximadamente 2% do total de casos. No entanto, o elevado número de casos de TBMR em prevalência no nosso país, os tempos muito prolongados de infecciosidade destes e a elevada expansão da resistência aos fármacos de 2ª linha, contribuem para se tornar um problema endémico. Assim, o controlo da tuberculose (TB) depende do diagnóstico precoce e consequentemente um início precoce de tratamento adequado de modo a reduzir as fontes de infecção e o risco de transmissão.
The emergence of resistance to drugs used to treat tuberculosis, and in particular multidrug-resistant tuberculosis (MDR-TB), has been a major threat to the effectiveness of its control. In Portugal, the proportion of incident cases of MDR-TB is within the median of Western European countries, accounting for approximately 2% of all cases. However, the high prevalence of MDR-TB in our country, its very long infectivity, and the high level of resistance to second-line drugs contribute to an endemic problem. Thus, tuberculosis (TB) control depends on early diagnosis and therefore early initiation of appropriate treatment in order to reduce sources of infection and the risk of transmission.
The emergence of resistance to drugs used to treat tuberculosis, and in particular multidrug-resistant tuberculosis (MDR-TB), has been a major threat to the effectiveness of its control. In Portugal, the proportion of incident cases of MDR-TB is within the median of Western European countries, accounting for approximately 2% of all cases. However, the high prevalence of MDR-TB in our country, its very long infectivity, and the high level of resistance to second-line drugs contribute to an endemic problem. Thus, tuberculosis (TB) control depends on early diagnosis and therefore early initiation of appropriate treatment in order to reduce sources of infection and the risk of transmission.
Descrição
Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2017
Palavras-chave
Tuberculose Tuberculose multiresistente Vírus da imunodeficiência humana Mycobacterium tuberculosis Doenças transmissíveis
