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Advisor(s)
Abstract(s)
A obesidade constitui uma crescente preocupação global, afetando significativamente a saúde
das pessoas e a economia mundial, estando associada a doenças graves como Diabetes Tipo 2,
problemas cardiovasculares e alguns tipos de cancros. A título adicional, prevê-se um
aumento em 167 milhões de pessoas obesas até 2025, sendo que o contexto pandémico
exacerbou o problema, especialmente na faixa etária mais jovem, devido a um estilo de vida
mais sedentário. O seu tratamento envolve recomendações não farmacológicas, como a
prática regular de exercício físico e uma dieta equilibrada, e algoritmos terapêuticos que,
muitas vezes, podem ter efeitos adversos significativos. Uma alternativa emergente está nas
plantas medicinais, que possuem eficácia comprovada e efeitos adversos mínimos. Essas
plantas têm sido utilizadas há milhares de anos, com os primeiros registros na Índia, China,
Egito, Grécia e Ásia Central.
O mercado de plantas medicinais tem experienciado um crescimento significativo e foi
avaliado em cerca de 84,6 biliões de dólares em 2020, com um crescimento anual esperado de
7,2% até 2028, sendo que a Europa é responsável por 36% da produção global. Com a
crescente consciencialização pública acerca do potencial de alternativas naturais para a saúde,
é esperado que o uso de plantas medicinais continue a aumentar. O avanço da tecnologia
melhorou a produção e extração de compostos ativos, contribuindo para a maior qualidade e
segurança dos produtos com a simultânea redução de custos e exploração abusiva de espécies.
As plantas medicinais podem auxiliar na perda de peso através de vários mecanismos, tais
como inibição da atividade da lipase pancreática, aumento da termogénese, inibição da
adipogénese, potencialização do metabolismo basal e redução do apetite. Muitas destas
plantas, sendo nesta monografia destacada a erva-mate, possuem propriedades antioxidantes e
anti-inflamatórias, que podem ser benéficas para condições associadas à obesidade.
Esta monografia tem o objetivo de explorar o uso potencial de plantas medicinais no
tratamento da obesidade e analisar a viabilidade de investimento neste nicho mercado em
expansão, oferecendo insights sobre oportunidades de investimento e inovação do setor
farmacêutico neste ramo.
Obesity is a growing global concern, significantly affecting people's health and the world economy, and is associated with serious diseases such as Type 2 Diabetes, cardiovascular problems and some types of cancer. Furthermore, an increase of 167 million obese people is predicted by 2025, and the pandemic context has exacerbated the problem, especially in the younger age group due to a more sedentary lifestyle. The treatment of obesity involves both non-pharmacological recommendations, such as regular exercise and a balanced diet, and therapeutic algorithms that can often have significant adverse effects. An emerging alternative lies in medicinal plants, which have proven efficacy and minimal adverse effects. These plants have been used for thousands of years, with the first records in India, China, Egypt, Greece, and Central Asia. The medicinal plants market has experienced significant growth and was valued at about $84.6 billion in 2020, with an expected annual growth of 7.2% through 2028, with Europe accounting for 36% of global production. With the growing public awareness about the potential of natural health alternatives, the use of medicinal plants is expected to continue increasing. Advances in technology have improved the production and extraction of active compounds, contributing to higher quality and safety of products with simultaneous reduction of costs and exploitation of species. Medicinal plants can aid in weight loss through various mechanisms, such as inhibiting pancreatic lipase activity, increasing thermogenesis, inhibiting adipogenesis, potentiating basal metabolism, and reducing appetite. Many of these plants, with yerba mate in particular, have antioxidant and anti-inflammatory properties, which may be beneficial for conditions associated with obesity. This monograph aims to explore the potential use of medicinal plants in the treatment of obesity and analyze the feasibility of investing in this expanding niche market, offering insights into investment and innovation opportunities for the pharmaceutical sector in this field.
Obesity is a growing global concern, significantly affecting people's health and the world economy, and is associated with serious diseases such as Type 2 Diabetes, cardiovascular problems and some types of cancer. Furthermore, an increase of 167 million obese people is predicted by 2025, and the pandemic context has exacerbated the problem, especially in the younger age group due to a more sedentary lifestyle. The treatment of obesity involves both non-pharmacological recommendations, such as regular exercise and a balanced diet, and therapeutic algorithms that can often have significant adverse effects. An emerging alternative lies in medicinal plants, which have proven efficacy and minimal adverse effects. These plants have been used for thousands of years, with the first records in India, China, Egypt, Greece, and Central Asia. The medicinal plants market has experienced significant growth and was valued at about $84.6 billion in 2020, with an expected annual growth of 7.2% through 2028, with Europe accounting for 36% of global production. With the growing public awareness about the potential of natural health alternatives, the use of medicinal plants is expected to continue increasing. Advances in technology have improved the production and extraction of active compounds, contributing to higher quality and safety of products with simultaneous reduction of costs and exploitation of species. Medicinal plants can aid in weight loss through various mechanisms, such as inhibiting pancreatic lipase activity, increasing thermogenesis, inhibiting adipogenesis, potentiating basal metabolism, and reducing appetite. Many of these plants, with yerba mate in particular, have antioxidant and anti-inflammatory properties, which may be beneficial for conditions associated with obesity. This monograph aims to explore the potential use of medicinal plants in the treatment of obesity and analyze the feasibility of investing in this expanding niche market, offering insights into investment and innovation opportunities for the pharmaceutical sector in this field.
Description
Trabalho Final de Mestrado Integrado, Ciências Farmacêuticas, 2023, Universidade de Lisboa, Faculdade de Farmácia.
Keywords
Plantas medicinais Emagrecimento Ilex paraguariensis Investimento Obesidade Mestrado Integrado - 2023