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Fasciculation-cramp syndrome preceding anterior horn cell disease : an intermediate syndrome?
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Orientador(es)
Resumo(s)
Cramp-fasciculation syndrome (cramp-FS) is an ill-defined condition with uncertain clinical limits. The authors studied a 55-year-old man with progressively more severe, widespread fasciculations and cramps during a 6-year-period. Mild progressive lower motor neuron loss, shown by motor unit number and multi-motor unit potential (MUP) analysis, developed during the 4 years after onset, which stabilised during a further 2-year follow-up. Cramp-FS is generally a benign syndrome, probably with several causations. Our patient developed a limited form of anterior horn cell degeneration perhaps representing a syndrome transitional with amyotrophic lateral sclerosis. Cramp-FS merits more detailed study.
Descrição
Copyright © 2012 by the BMJ Publishing Group Ltd. All rights reserved.
Palavras-chave
Amyotrophic lateral sclerosis Cramp-fasciculation syndrome Fasciculations Myokymia EMG Motor neuron disease
Contexto Educativo
Citação
J Neurol Neurosurg Psychiatry 2011;82:459-461