A carregar...
Publicação
Coinfeção tuberculose/COVID-19 : revisão da literatura a propósito de uma série de casos clínicos
| Nome: | Descrição: | Tamanho: | Formato: | |
|---|---|---|---|---|
| 2.05 MB | Adobe PDF |
Autores
Orientador(es)
Resumo(s)
A pandemia da doença do coronavírus 2019 (COVID-19) tornou-se um desafio global, afetando milhões de pessoas no mundo. Entre as coinfeções que podem afetar o resultado desses doentes, é importante considerar a tuberculose (TB), que ainda é uma das principais causas de mortalidade por doenças infeciosas. A TB afeta principalmente os pulmões e as vias respiratórias, assim como a COVID-19, e apresenta sintomas semelhantes como tosse, febre, dispneia, podendo passar despercebida. Portugal é um país onde a TB é endémica, e devido à escassez de estudos sobre a coinfeção TB e COVID-19, este estudo retrospetivo abordou 15 casos clínicos de doentes internados no Serviço de Infeciologia, no Hospital Beatriz Ângelo, em Loures. Foram analisadas as características demográficas, epidemiológicas e clínicas, com o objetivo de caracterizar essa população e destacar a relação entre ambas as doenças. Os resultados obtidos foram comparados com séries internacionais publicadas. Concluiu-se que os doentes com coinfeção TB e COVID-19 devem ser avaliados com urgência, tendo em consideração a sobreposição de sinais e sintomas. Suspeitar da presença de ambas as doenças permite o início precoce do tratamento, melhorando o prognóstico, evitando complicações, reduzindo a duração do internamento e aliviando a pressão sobre os serviços de saúde. Considera-se que este estudo possa complementar os dados atualmente disponíveis, reforçando o interesse do mesmo. Além disso, pode servir como ponto de partida para futuros estudos longitudinais observacionais, representativos e multicêntricos, a fim de avaliar um maior número de doentes, proporcionando uma melhor compreensão das interações entre as duas doenças e otimizando o cuidado dos doentes.
The coronavirus disease 2019 (COVID-19) pandemic has become a global challenge, affecting millions of people in the world. Among the various co-infections that can affect the outcome of these patients, it is important to consider tuberculosis (TB), as it is still one of the main causes of mortality from infectious diseases. TB mainly affects the lungs and respiratory tract, just like COVID-19, and presents similar symptoms, such as cough, fever, dyspnea, and can go unnoticed. Portugal is a country where TB is endemic, and due to the scarcity of studies on TB and COVID-19 co-infection, this retrospective study addressed 15 clinical cases of patients admifed to the Infectious Diseases Service, at Hospital Beatriz Ângelo, in Loures. Demographic, epidemiological and clinical characteristics were analyzed, with the aim of characterizing this population and highlighting the relationship between both diseases. The results obtained were compared with published international series. It was concluded that patients with TB and COVID-19 co-infection need to be evaluated urgently, taking into account the overlapping of signs and symptoms. Suspecting the presence of both diseases allows early treatment to begin, improving the prognosis, avoiding complications, reducing the length of hospital stay and relieving pressure on health services. It is considered that this study can complement the currently available data, reinforcing its interest. Furthermore, it can serve as a starting point for future observational, representative and multicenter longitudinal studies, in order to evaluate a greater number of patients, providing a befer understanding of the interactions between the two diseases and optimizing patient care.
The coronavirus disease 2019 (COVID-19) pandemic has become a global challenge, affecting millions of people in the world. Among the various co-infections that can affect the outcome of these patients, it is important to consider tuberculosis (TB), as it is still one of the main causes of mortality from infectious diseases. TB mainly affects the lungs and respiratory tract, just like COVID-19, and presents similar symptoms, such as cough, fever, dyspnea, and can go unnoticed. Portugal is a country where TB is endemic, and due to the scarcity of studies on TB and COVID-19 co-infection, this retrospective study addressed 15 clinical cases of patients admifed to the Infectious Diseases Service, at Hospital Beatriz Ângelo, in Loures. Demographic, epidemiological and clinical characteristics were analyzed, with the aim of characterizing this population and highlighting the relationship between both diseases. The results obtained were compared with published international series. It was concluded that patients with TB and COVID-19 co-infection need to be evaluated urgently, taking into account the overlapping of signs and symptoms. Suspecting the presence of both diseases allows early treatment to begin, improving the prognosis, avoiding complications, reducing the length of hospital stay and relieving pressure on health services. It is considered that this study can complement the currently available data, reinforcing its interest. Furthermore, it can serve as a starting point for future observational, representative and multicenter longitudinal studies, in order to evaluate a greater number of patients, providing a befer understanding of the interactions between the two diseases and optimizing patient care.
Descrição
Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2024
Palavras-chave
Coinfeção Tuberculose COVID-19 Doenças transmissíveis