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Bleb morphology of glaucoma drainage devices on magnetic resonance imaging

dc.contributor.authorCorreia Barão, Rafael
dc.contributor.authorBerhanu, David
dc.contributor.authorMatos, Diogo Bernardo
dc.contributor.authorBarata, Andre
dc.contributor.authorSousa, Rita
dc.contributor.authorPinto, Luis
dc.date.accessioned2023-11-22T14:51:11Z
dc.date.available2023-11-22T14:51:11Z
dc.date.issued2023
dc.description© 2023 The Authors. Acta Ophthalmologica published by John Wiley & Sons Ltd on behalf of Acta Ophthalmologica Scandinavica Foundation. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.pt_PT
dc.description.abstractPurpose: To evaluate bleb morphology features of different glaucoma drainage devices (GDD) using magnetic resonance imaging (MRI). Materials and methods: Prospective cohort study of GDD and bleb morphology in consecutive glaucoma patients implanted with Ahmed Glaucoma Valve (AGV), Paul Glaucoma Implant (PGI), Baerveldt Glaucoma Implant (BGI) and Ahmed ClearPath (ACP) devices. Thirty-six eyes from 30 consecutive patients underwent standardized GDD implantation followed by MRI at least 1 month after surgery. Main outcomes included bleb volume and endplate position relative to the optic nerve. Secondary outcomes included intraocular pressure (IOP), medication and surgical complications during a 12-month follow-up. Results: Seven eyes were implanted with the AGV (19%), 5 with BGI (14%), 16 with PGI (44%) and 8 with ACP (22%). MRI scans were obtained 85 ± 66 days after surgery. Mean total bleb volume was 563 ± 390 mm3 . This bleb volume was inversely correlated with early post-operative IOP (day 7; rs = -0.3326, p = 0.0475) but positively correlated with IOP at 12 months (rs = 0.3592, p = 0.0341). No significant difference in total bleb volume was found between GDD types (p = 0.1223). A double-layered bleb was observed in 34 eyes (94%). The inferior bleb volume was significantly larger in PGI devices versus other GDD types (380 ± 205 vs. 193 ± 161 mm3 ; p = 0.0043). Distance from the endplate to the optic nerve was 9.5 ± 4.0 mm, similar across GDDs (p = 0.2519). Conclusions: Double-layered blebs are a common finding with GDDs. Bleb volume showed different correlations with IOP at distinct timepoints and the PGI device formed larger blebs. A standardized GDD implantation technique ensures a safe distance from the GDD endplate to the optic nerve.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationActa Ophthalmol. 2023 Nov;101(7):789-796pt_PT
dc.identifier.doi10.1111/aos.15668pt_PT
dc.identifier.eissn1755-3768
dc.identifier.issn1755-375X
dc.identifier.urihttp://hdl.handle.net/10451/60748
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWileypt_PT
dc.relation.publisherversionhttps://onlinelibrary.wiley.com/journal/17553768pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectAqueous shuntpt_PT
dc.subjectGlaucomapt_PT
dc.subjectGlaucoma surgerypt_PT
dc.subjectLong tubept_PT
dc.subjectMagnetic resonance imagingpt_PT
dc.subjectOrbitpt_PT
dc.titleBleb morphology of glaucoma drainage devices on magnetic resonance imagingpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage796pt_PT
oaire.citation.issue7pt_PT
oaire.citation.startPage789pt_PT
oaire.citation.titleActa Ophthalmologicapt_PT
oaire.citation.volume101pt_PT
person.familyNameCorreia Barão
person.familyNameAlves Berhanu
person.familyNameMatos
person.familyNameBarata
person.familyNameSousa
person.familyNameAbegão Pinto
person.givenNameRafael
person.givenNameDavid
person.givenNameDiogo Bernardo
person.givenNameAndre
person.givenNameRita
person.givenNameLuis
person.identifier1047141
person.identifier.ciencia-idB912-8429-153C
person.identifier.ciencia-idF216-4AFA-8E65
person.identifier.orcid0000-0002-3102-1969
person.identifier.orcid0000-0003-1851-7182
person.identifier.orcid0000-0002-6929-4524
person.identifier.orcid0000-0002-0976-5603
person.identifier.orcid0000-0002-6096-8182
person.identifier.orcid0000-0002-9960-7579
person.identifier.scopus-author-id57192198642
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication1d6be9e4-74a8-43e2-9e87-ea67c834f019
relation.isAuthorOfPublication297f2467-09c4-407c-ba80-91ec9db67cdb
relation.isAuthorOfPublication605188d8-40e6-434d-bedd-650f1ff46519
relation.isAuthorOfPublicationa8788f82-1531-4cba-a941-f4a501f4ae81
relation.isAuthorOfPublication79a4bc80-4fd2-470b-8ef1-068cc3aa1107
relation.isAuthorOfPublicationac0af1be-ba49-41eb-9e2f-8d22afb92af0
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