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Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020–2030

2022Artigo científico Acesso aberto
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dc.contributor.authorZare Jeddi, Maryam
dc.contributor.authorHopf, Nancy B.
dc.contributor.authorLouro, Henriqueta
dc.contributor.authorViegas, Susana
dc.contributor.authorGalea, Karen S.
dc.contributor.authorPasanen-Kase, Robert
dc.contributor.authorSantonen, Tiina
dc.contributor.authorMustieles, Vicente
dc.contributor.authorFernandez, Mariana F.
dc.contributor.authorVerhagen, Hans
dc.contributor.authorBopp, Stephanie K.
dc.contributor.authorAntignac, Jean Philippe
dc.contributor.authorDavid, Arthur
dc.contributor.authorMol, Hans
dc.contributor.authorBarouki, Robert
dc.contributor.authorAudouze, Karine
dc.contributor.authorDuca, Radu-Corneliu
dc.contributor.authorFantke, Peter
dc.contributor.authorScheepers, Paul
dc.contributor.authorGhosh, Manosij
dc.contributor.authorVan Nieuwenhuyse, An
dc.contributor.authorLobo Vicente, Joana
dc.contributor.authorTrier, Xenia
dc.contributor.authorRambaud, Loïc
dc.contributor.authorFillol, Clémence
dc.contributor.authorDenys, Sebastien
dc.contributor.authorConrad, André
dc.contributor.authorKolossa-Gehring, Marike
dc.contributor.authorPaini, Alicia
dc.contributor.authorArnot, Jon
dc.contributor.authorSchulze, Florian
dc.contributor.authorJones, Kate
dc.contributor.authorSepai, Ovnair
dc.contributor.authorAli, Imran
dc.contributor.authorBrennan, Lorraine
dc.contributor.authorBenfenati, Emilio
dc.contributor.authorCubadda, Francesco
dc.contributor.authorMantovani, Alberto
dc.contributor.authorBartonova, Alena
dc.contributor.authorConnolly, Alison
dc.contributor.authorSlobodnik, Jaroslav
dc.contributor.authorBruinen de Bruin, Yuri
dc.contributor.authorvan Klaveren, Jacob
dc.contributor.authorPalmen, Nicole
dc.contributor.authorDirven, Hubert
dc.contributor.authorHusøy, Trine
dc.contributor.authorThomsen, Cathrine
dc.contributor.authorVirgolino, Ana
dc.contributor.authorRöösli, Martin
dc.contributor.authorGant, Tim
dc.contributor.authorvon Goetz, Natalie
dc.contributor.authorBessems, Jos
dc.date.accessioned2022-09-13T10:35:10Z
dc.date.available2022-09-13T10:35:10Z
dc.date.issued2022
dc.description© 2022 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)pt_PT
dc.description.abstractHuman biomonitoring (HBM) is a crucial approach for exposure assessment, as emphasised in the European Commission's Chemicals Strategy for Sustainability (CSS). HBM can help to improve chemical policies in five major key areas: (1) assessing internal and aggregate exposure in different target populations; 2) assessing exposure to chemicals across life stages; (3) assessing combined exposure to multiple chemicals (mixtures); (4) bridging regulatory silos on aggregate exposure; and (5) enhancing the effectiveness of risk management measures. In this strategy paper we propose a vision and a strategy for the use of HBM in chemical regulations and public health policy in Europe and beyond. We outline six strategic objectives and a roadmap to further strengthen HBM approaches and increase their implementation in the regulatory risk assessment of chemicals to enhance our understanding of exposure and health impacts, enabling timely and targeted policy interventions and risk management. These strategic objectives are: 1) further development of sampling strategies and sample preparation; 2) further development of chemical-analytical HBM methods; 3) improving harmonisation throughout the HBM research life cycle; 4) further development of quality control / quality assurance throughout the HBM research life cycle; 5) obtain sustained funding and reinforcement by legislation; and 6) extend target-specific communication with scientists, policymakers, citizens and other stakeholders. HBM approaches are essential in risk assessment to address scientific, regulatory and societal challenges. HBM requires full and strong support from the scientific and regulatory domain to reach its full potential in public and occupational health assessment and in regulatory decision-making.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationEnviron Int. 2022 Aug 28;168:107476pt_PT
dc.identifier.doi10.1016/j.envint.2022.107476pt_PT
dc.identifier.eissn1873-6750
dc.identifier.issn0160-4120
dc.identifier.urihttp://hdl.handle.net/10451/54441
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/journal/environment-internationalpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectChemicals mixturespt_PT
dc.subjectCircular economypt_PT
dc.subjectData governancept_PT
dc.subjectHuman biomonitoringpt_PT
dc.subjectOne substance-one assessmentpt_PT
dc.subjectZero Pollution Ambitionpt_PT
dc.titleDeveloping human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020–2030pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleEnvironment Internationalpt_PT
oaire.citation.volume168pt_PT
person.familyNameVirgolino
person.givenNameAna
person.identifier.ciencia-id1A10-C261-AC8E
person.identifier.orcid0000-0003-0428-6643
person.identifier.scopus-author-id56538593800
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationa6f60fb1-2107-4c7a-b964-2482e43dcc54
relation.isAuthorOfPublication.latestForDiscoverya6f60fb1-2107-4c7a-b964-2482e43dcc54

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