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Diagnosis of giant cell arteritis

2020Artigo científico Acesso aberto
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dc.contributor.authorLuqmani, Raashid Ahmed
dc.contributor.authorMartins Martinho, Joana
dc.contributor.authorPonte, Cristina
dc.date.accessioned2021-03-08T17:00:27Z
dc.date.available2021-03-08T17:00:27Z
dc.date.issued2020
dc.description© The Author(s) 2020. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved.pt_PT
dc.description.abstractGCA is the most common form of primary systemic vasculitis affecting older people. It is considered a clinical emergency because it can lead to irreversible blindness in around 20% of untreated cases. High doses of glucocorticoids should be initiated promptly to prevent disease-related complications; however, glucocorticoids therapy usually results in significant toxicity. Therefore, correct diagnosis is crucial. For many years, temporal artery biopsy has been considered the diagnostic ‘gold standard’ for GCA, but it has many limitations (including low sensitivity). US has proven to be effective for diagnosing GCA and can reliably replace temporal artery biopsy in particular clinical settings. In cases of suspected GCA with large-vessel involvement, other imaging modalities can be used for diagnosis (e.g. CT and PET). Here we review the current evidence for each diagnostic modality and propose an algorithm to diagnose cranial-GCA in a setting with rapid access to high quality US.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRheumatology (Oxford). 2020 May 1;59(Suppl 3):iii5-iii16.pt_PT
dc.identifier.doi10.1093/rheumatology/kez553pt_PT
dc.identifier.eissn1462-0332
dc.identifier.issn1462-0324
dc.identifier.urihttp://hdl.handle.net/10451/46728
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherOxford University Presspt_PT
dc.relation.publisherversionhttps://academic.oup.com/rheumatologypt_PT
dc.subjectGiant cell arteritispt_PT
dc.subjectDiagnosispt_PT
dc.subjectTemporal artery biopsypt_PT
dc.subjectUltrasoundpt_PT
dc.subjectMagnetic resonancept_PT
dc.subjectComputed tomographypt_PT
dc.subjectPositron emission tomographypt_PT
dc.subjectImagingpt_PT
dc.titleDiagnosis of giant cell arteritispt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPageiii16pt_PT
oaire.citation.issueSupplement_3pt_PT
oaire.citation.startPageiii5pt_PT
oaire.citation.titleRheumatologypt_PT
oaire.citation.volume59pt_PT
person.familyNamePonte
person.givenNameCristina
person.identifier.ciencia-id3713-901B-4493
person.identifier.orcid0000-0002-3989-1192
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication22483f4f-a4d7-48f5-9fae-cc5ae926528a
relation.isAuthorOfPublication.latestForDiscovery22483f4f-a4d7-48f5-9fae-cc5ae926528a

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