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Relação entre endometriose e síndrome do intestino irritável
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A endometriose e a síndrome do intestino irritável (SII) são duas entidades muito prevalentes nas mulheres em idade fértil. Constituem ainda duas importantes causas de dor pélvica crónica nesta população. Apesar disto, os seus mecanismos são pouco compreendidos e as opções terapêuticas existentes são limitadas e pouco satisfatórias. Recentemente, têm surgido vários estudos que sugerem uma associação entre estas duas condições. Tendo isto em conta, no presente trabalho pretende-se realizar uma revisão bibliográfica da evidência mais atual sobre este tema, bem como a realização de um estudo observacional transversal, com o objetivo de determinar qual a prevalência de SII nas mulheres com endometriose. Para tal, foi elaborado um questionário online para a colheita de dados. Um total de 1373 mulheres completaram o questionário. Após a aplicação dos critérios de exclusão - a ausência de diagnóstico prévio de endometriose realizado por um profissional de saúde - foram incluídas 1191 participantes. O diagnóstico de endometriose foi estabelecido com base no diagnóstico médico prévio. O diagnóstico de SII foi considerado através de dois métodos: 1) diagnóstico anterior médico; 2) cumprimento dos critérios de ROMA IV. De acordo com os nossos resultados, a prevalência de SII nas doentes com endometriose foi de 60,5%. Estes dados estão de acordo com os de outros estudos semelhantes. Apesar de a evidência disponível ainda ser muito limitada, esta descoberta permite o desenvolvimento de novas abordagens terapêuticas no controlo da dor na endometriose.
Endometriosis and Irritable Bowel Syndrome (IBS) are two common diseases in women of reproductive age. They are also two major causes of chronic pelvic pain in this population. Despite this, its mechanisms are poorly understood and the available therapeutic options are quite limited and unsatisfactory. Recently there have been several studies suggesting an association between these two conditions. Bearing this in mind, the present work intends to carry out a narrative review of the most updated evidence on this subject, as well as to conduct a descriptive cross-sectional study to determine the prevalence of IBS in women with endometriosis. Data was collected through an online questionnaire. A total of 1373 women completed the questionnaire. After applying the exclusion criteria - the absence of a previous diagnosis of endometriosis - 1191 participants were included. Endometriosis was identified based on previous medical diagnosis. The IBS diagnosis was established by two different methods: 1) previous medical diagnosis; 2) fulfillment of ROME IV criteria. According to our results, the prevalence of IBS in women with endometriosis was 60.5%. These data are in agreement with similar studies. Even though available evidence is still very limited, this finding allows the development of new therapeutic approaches for the management of endometriosis’ associated pain.
Endometriosis and Irritable Bowel Syndrome (IBS) are two common diseases in women of reproductive age. They are also two major causes of chronic pelvic pain in this population. Despite this, its mechanisms are poorly understood and the available therapeutic options are quite limited and unsatisfactory. Recently there have been several studies suggesting an association between these two conditions. Bearing this in mind, the present work intends to carry out a narrative review of the most updated evidence on this subject, as well as to conduct a descriptive cross-sectional study to determine the prevalence of IBS in women with endometriosis. Data was collected through an online questionnaire. A total of 1373 women completed the questionnaire. After applying the exclusion criteria - the absence of a previous diagnosis of endometriosis - 1191 participants were included. Endometriosis was identified based on previous medical diagnosis. The IBS diagnosis was established by two different methods: 1) previous medical diagnosis; 2) fulfillment of ROME IV criteria. According to our results, the prevalence of IBS in women with endometriosis was 60.5%. These data are in agreement with similar studies. Even though available evidence is still very limited, this finding allows the development of new therapeutic approaches for the management of endometriosis’ associated pain.
Descrição
Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2023
Palavras-chave
Endometriose Síndrome do intestino irritável Dor pélvica crónica Hipersensibilidade visceral Inflamação crónica Ginecologia