A carregar...
Publicação
Clinical and psychological profile of Takotsubo syndrome
| Nome: | Descrição: | Tamanho: | Formato: | |
|---|---|---|---|---|
| 1.63 MB | Adobe PDF |
Orientador(es)
Resumo(s)
Introdução: A Síndrome de takotsubo (TTS) constitui uma condição aguda reversível caracterizada por uma disfunção sistólica ventricular esquerda (LV) e achados eletrocardiográficos que mimetizam o enfarte agudo do miocárdio (AMI). A principal característica da TTS é a sua associação com um evento físico ou emocional precipitante.
Objetivo: Caracterizar o perfil clínico de uma amostra populacional portuguesa de doentes diagnosticados com TTS, com especial ênfase nos dados sociodemográficos e em eventuais eventos psicológicos e/ou físicos precedentes anotados na história clínica.
Métodos: Estudo retrospetivo com componente descritiva que incluiu 54 doentes diagnosticados com TTS entre dezembro de 2005 e dezembro de 2018 num hospital terciário. Foram colhidos dados demográficos, socioeconómicos, psicológicos, clínicos, laboratoriais, eletrocardiográficos e ecocardiográficos. O processamento estatístico foi feito com os programas SPSS 26.0 (IBM SPSS; United States) e Office 2016 (Microsoft; United States).
Resultados: Os doentes foram predominantemente mulheres (87,0%), com uma idade média de 67 anos e alta prevalência de fatores de risco cardiovasculares (CV). Um subconjunto importante de doentes apresentava distúrbios psiquiátricos agudos (5,6%) e crónicos (37,7%). Na maioria dos doentes foram identificados eventos precipitantes emocionais (35,2%), físicos (16,7%) ou ambos (22,2%). As mulheres relataram mais adversidades a nível interpessoal, enquanto os homens relataram mais problemas a nível profissional.
Conclusão: Este estudo de uma população hospitalar portuguesa demonstra a heterogeneidade do espectro clínico da TTS, identificando-se na maioria dos casos estímulos emocionais e/ou físicos como fatores precipitantes. Reforça-se, assim, a necessidade de compreender a TTS como uma síndrome clínica complexa, e a vantagem de um acompanhamento interdisciplinar.
Introduction: Takotsubo syndrome (TTS) is an acute reversible condition characterized by transient left ventricular (LV) systolic dysfunction and electrocardiographic changes that mimic acute myocardial infarction (AMI). A hallmark of TTS is its association with a preceding emotional or physical event. Objectives: To characterize the clinical profile a sample of portuguese patients diagnosed with TTS, with special emphasis on socio demographic data, and eventual preceding psychological and/or physical events noted from the clinical history. Methods: We conducted a retrospective cohort with descriptive components that included 54 patients diagnosed with TTS between december 2005 and december 2018 in a tertiary hospital. Data was collected on demographic, socioeconomic, psychological, clinical, laboratory, electrocardiographic and echocardiographic findings. Statistical processing was done with SPSS 26.0 (IBM SPSS; United States) and the multimedia software package, Office 2016 (Microsoft; United States). Results: Patients were predominantly women (87,0%), with a mean age of 67 years, and a high prevalence of cardiovascular (CV) risk factors. An important subset of patients had acute (5,6%) and chronic (37,7%) psychiatric disorders. In the majority of patients a preceding event was identified: emotional (35,2%), physical (16,7%) or both (22,2%). Regarding specific emotional stressors, women reported more in interpersonal areas, whereas men reported more work related problems. Conclusions: Our analysis of a sample of a portuguese population demonstrates the heterogeneous clinical spectrum of TTS, with the majority of cases having an emotional and/or physical trigger identified as a predisposing factor. This emphasizes the need to understand TTS as a thoroughgoing clinical syndrome and validates the advantage of an interdisciplinar follow-up.
Introduction: Takotsubo syndrome (TTS) is an acute reversible condition characterized by transient left ventricular (LV) systolic dysfunction and electrocardiographic changes that mimic acute myocardial infarction (AMI). A hallmark of TTS is its association with a preceding emotional or physical event. Objectives: To characterize the clinical profile a sample of portuguese patients diagnosed with TTS, with special emphasis on socio demographic data, and eventual preceding psychological and/or physical events noted from the clinical history. Methods: We conducted a retrospective cohort with descriptive components that included 54 patients diagnosed with TTS between december 2005 and december 2018 in a tertiary hospital. Data was collected on demographic, socioeconomic, psychological, clinical, laboratory, electrocardiographic and echocardiographic findings. Statistical processing was done with SPSS 26.0 (IBM SPSS; United States) and the multimedia software package, Office 2016 (Microsoft; United States). Results: Patients were predominantly women (87,0%), with a mean age of 67 years, and a high prevalence of cardiovascular (CV) risk factors. An important subset of patients had acute (5,6%) and chronic (37,7%) psychiatric disorders. In the majority of patients a preceding event was identified: emotional (35,2%), physical (16,7%) or both (22,2%). Regarding specific emotional stressors, women reported more in interpersonal areas, whereas men reported more work related problems. Conclusions: Our analysis of a sample of a portuguese population demonstrates the heterogeneous clinical spectrum of TTS, with the majority of cases having an emotional and/or physical trigger identified as a predisposing factor. This emphasizes the need to understand TTS as a thoroughgoing clinical syndrome and validates the advantage of an interdisciplinar follow-up.
Descrição
Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2022
Palavras-chave
Síndrome de Takotsubo Emotional triggers Physical triggers