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A systematic review and meta-analysis of the incidence of acute aortic dissections in population-based studies

2022Journal article Restricted access
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dc.contributor.authorMelo, Ryan
dc.contributor.authorOliveira Mourão, Mariana
dc.contributor.authorCaldeira, Daniel
dc.contributor.authorAlves, Mariana
dc.contributor.authorLopes, Alice
dc.contributor.authorDuarte, António
dc.contributor.authorFernandes E Fernandes, Ruy
dc.contributor.authorPedro, Luís M
dc.date.accessioned2022-06-24T11:41:26Z
dc.date.available2022-06-24T11:41:26Z
dc.date.issued2022
dc.descriptionCopyright © 2021 by the Society for Vascular Surgery. Published by Elsevier Inc.pt_PT
dc.description.abstractObjective: To perform a systematic review and meta-analysis of all population-based studies reporting on incidence of acute aortic dissections (AADs). Methods: We searched the MEDLINE, EMBASE, CENTRAL, and Open Grey databases from inception to August 2020 for population-based studies reporting on the incidence of AAD. A systematic review was conducted following the PRISMA guidelines using a registered protocol (CRD42020204007). Data were pooled using a random effects model of proportions using Freeman-Tukey double arcsine transformation. The main outcome was the incidence of AAD. Secondary outcomes were incidence type A aortic dissections (TAAD) and type B aortic dissections (TBAD), the incidence of aortic dissection repair and medical management, and the incidence of in-hospital mortality. In addition, we estimated the proportion of aortic dissection repair and mortality (in hospital, overall and specific mortality according to subtype) among patients with AAD. Results: Thirty-three studies were included. The pooled incidence of AADs was 4.8 per 100,000 individuals/year (95% confidence interval [CI], 3.6-6.1). The incidence of TAAD was 3.0 per 100,000/year (95% CI, 1.8-4.4) and the incidence of TBAD was 1.6 per 100,000/year (95% CI, 1.1-2.2). The incidence of AAD needing repair was 1.4 per 100,000/year (95% CI, 1.0-2.0) (or 1.4 [95% CI, 1.2-1.7] for TAAD and 0.4 [95% CI, 0.2-0.7] for TBAD). The incidence of medically managed AAD was 3.4 per 100,000/year (95% CI, 2.4-4.5). The incidence of in-hospital death owing to AAD was 1.3 per 100,000 individuals/year (95% CI, 0.9-1.9), 1.0 (95% CI, 0.6-1.4; I2 = 97%) for TAAD, and 0.3 for TBAD (95% CI, 0.2-0.4; I2 = 96%). Conclusions: A global estimate regarding the incidence rate of AADs was achieved. The incidence of AAD varied significantly between study designs and geographical regions. More accurate information on AAD epidemiology is crucial for public health decisions, clinical understanding, and healthcare management.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationJ Vasc Surg. 2022 Feb;75(2):709-720pt_PT
dc.identifier.doi10.1016/j.jvs.2021.08.080pt_PT
dc.identifier.eissn1097-6809
dc.identifier.issn0741-5214
dc.identifier.urihttp://hdl.handle.net/10451/53478
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/journal/journal-of-vascular-surgerypt_PT
dc.subjectAcute aortic dissectionspt_PT
dc.subjectAortic dissectionspt_PT
dc.subjectEpidemiologic studypt_PT
dc.subjectIncidencept_PT
dc.subjectMeta-analysispt_PT
dc.subjectThoracic aortic dissectionspt_PT
dc.titleA systematic review and meta-analysis of the incidence of acute aortic dissections in population-based studiespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage720pt_PT
oaire.citation.issue2pt_PT
oaire.citation.startPage709pt_PT
oaire.citation.titleJournal of Vascular Surgerypt_PT
oaire.citation.volume75pt_PT
person.familyNameGouveia e Melo
person.familyNameOliveira Mourão
person.familyNameCaldeira
person.familyNameAlves
person.familyNameLopes
person.familyNameFernandes e Fernandes
person.familyNamePedro
person.givenNameRyan
person.givenNameMariana
person.givenNameDaniel
person.givenNameMariana
person.givenNameAlice
person.givenNameRuy
person.givenNameLuís
person.identifier1153684
person.identifier.ciencia-id211B-B548-CE4E
person.identifier.ciencia-idAA19-EC35-8D01
person.identifier.ciencia-id0718-09A9-D4EA
person.identifier.ciencia-id8D12-0BD7-11B5
person.identifier.ciencia-idB710-641D-77AD
person.identifier.ciencia-id0B14-1812-24DC
person.identifier.orcid0000-0001-8327-6384
person.identifier.orcid0000-0002-9305-7289
person.identifier.orcid0000-0002-2520-5673
person.identifier.orcid0000-0002-1369-8423
person.identifier.orcid0000-0002-1957-7614
person.identifier.orcid0000-0003-1619-8851
person.identifier.orcid0000-0003-4310-9324
person.identifier.ridO-3034-2016
person.identifier.scopus-author-id36623384200
person.identifier.scopus-author-id56591535500
person.identifier.scopus-author-id57203041538
person.identifier.scopus-author-id39761284300
person.identifier.scopus-author-id7004454630
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
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