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Circular RNA-centered regulatory networks in the physiopathology of cardiovascular diseases

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dc.contributor.authorGabriel, André F.
dc.contributor.authorCosta, Marina C.
dc.contributor.authorEnguita, Francisco J.
dc.date.accessioned2022-09-07T13:54:20Z
dc.date.available2022-09-07T13:54:20Z
dc.date.issued2020
dc.description© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).pt_PT
dc.description.abstractNon-coding regulatory RNAs are generated as a core output of the eukaryotic genomes, being essential players in cell biology. At the organism level, they are key functional actors in those tissues and organs with limited proliferation capabilities such as the heart. The role of regulatory networks mediated by non-coding RNAs in the pathophysiology of cardiovascular conditions is starting to be unveiled. However, a deeper knowledge of the functional interactions among the diverse non-coding RNA families and their phenotypic consequences is required. This review presents the current knowledge about the functional crosstalk between circRNAs and other biomolecules in the framework of the cardiovascular diseases.pt_PT
dc.description.sponsorshipThis work is supported by COST (European Cooperation in Science and Technology) Action EU-CardioRNA CA17129 and Portuguese Foundation for Science and Technology (FCT) under the framework of the research grant PTDC-MED-GEN-29389-2017.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationInt J Mol Sci. 2020 Jan 10;21(2):456pt_PT
dc.identifier.doi10.3390/ijms21020456pt_PT
dc.identifier.eissn1422-0067
dc.identifier.issn1661-6596
dc.identifier.urihttp://hdl.handle.net/10451/54354
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationPTDC-MED-GEN-29389-2017pt_PT
dc.relation.publisherversionhttps://www.mdpi.com/journal/ijmspt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectRNA regulatory networkspt_PT
dc.subjectCardiovascular diseasespt_PT
dc.subjectcircRNAspt_PT
dc.subjectmiRNAspt_PT
dc.subjectnon-coding RNApt_PT
dc.titleCircular RNA-centered regulatory networks in the physiopathology of cardiovascular diseasespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue2pt_PT
oaire.citation.titleInternational Journal of Molecular Sciencespt_PT
oaire.citation.volume21pt_PT
person.familyNameGabriel
person.familyNameCosta
person.familyNameEnguita
person.givenNameAndré Filipe Gonçalves
person.givenNameMarina
person.givenNameFrancisco J.
person.identifier887495
person.identifier173306
person.identifier.ciencia-id671C-AFF6-AF28
person.identifier.ciencia-id6818-7810-6CEC
person.identifier.ciencia-idB215-8D49-3218
person.identifier.orcid0000-0002-6565-1600
person.identifier.orcid0000-0001-9020-7539
person.identifier.orcid0000-0002-8072-8557
person.identifier.ridO-1710-2014
person.identifier.ridA-2347-2009
person.identifier.scopus-author-id57196534877
person.identifier.scopus-author-id55453276400
person.identifier.scopus-author-id6602119231
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication41b20e24-4358-467c-a6d8-c7eb53d9ea87
relation.isAuthorOfPublicationc4dcab9e-b873-4587-bb30-5203af150404
relation.isAuthorOfPublicationa101dbd4-6bf5-4546-882e-e2596eddb6b4
relation.isAuthorOfPublication.latestForDiscoverya101dbd4-6bf5-4546-882e-e2596eddb6b4

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