Intravital imaging of host–parasite interactions in skin and adipose tissues

De Niz, Mariana; Meehan, Gavin R.; Brancucci, Nicolas M. B.; Marti, Matthias; Rotureau, Brice; Figueiredo, Luisa M.; Frischknecht, Friedrich

http://hdl.handle.net/10451/52789

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Authors

De Niz, Mariana

Meehan, Gavin R.

Brancucci, Nicolas M. B.

Marti, Matthias

Rotureau, Brice

Figueiredo, Luisa M.

Frischknecht, Friedrich

Abstract(s)

Intravital microscopy allows the visualisation of how pathogens interact with host cells and tissues in living animals in real time. This method has enabled key advances in our understanding of host-parasite interactions under physiological conditions. A combination of genetics, microscopy techniques, and image analysis have recently facilitated the understanding of biological phenomena in living animals at cellular and subcellular resolution. In this review, we summarise findings achieved by intravital microscopy of the skin and adipose tissues upon infection with various parasites, and we present a view into possible future applications of this method.

Description

© 2019 The Authors Cellular Microbiology Published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.