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Mixed connective tissue disease : state of the art on clinical practice guidelines

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dc.contributor.authorChaigne, Benjamin
dc.contributor.authorScirè, Carlo Alberto
dc.contributor.authorTalarico, Rosaria
dc.contributor.authorAlexander, Tobias
dc.contributor.authorAmoura, Zahir
dc.contributor.authorAvcin, Tadej
dc.contributor.authorBeretta, Lorenzo
dc.contributor.authorDoria, Andrea
dc.contributor.authorGuffroy, Aurelien
dc.contributor.authorGuimarães, Vera
dc.contributor.authorHachulla, Éric
dc.contributor.authorKrieg, Thomas
dc.contributor.authorLaunay, David
dc.contributor.authorLepri, Gemma
dc.contributor.authorMoinzadeh, Pia
dc.contributor.authorMüller-Ladner, Ulf
dc.contributor.authorRednic, Simona
dc.contributor.authorRodrigues, Ana
dc.contributor.authorTas, Sander W
dc.contributor.authorVan Vollenhoven, Ronald F
dc.contributor.authorVieira, Ana
dc.contributor.authorBombardieri, Stefano
dc.contributor.authorFonseca, João Eurico
dc.contributor.authorGaletti, Ilaria
dc.contributor.authorSchneider, Matthias
dc.contributor.authorSmith, Vanessa
dc.contributor.authorCutolo, Maurizio
dc.contributor.authorMosca, Marta
dc.contributor.authorFischer-Betz, Rebecca
dc.date.accessioned2021-03-11T16:38:53Z
dc.date.available2021-03-11T16:38:53Z
dc.date.issued2019
dc.description© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.pt_PT
dc.description.abstractMixed connective tissue disease (MCTD) is a complex overlap disease with features of different autoimmune connective tissue diseases (CTDs) namely systemic sclerosis, poly/dermatomyositis and systemic lupus erythematous in patients with antibodies targeting the U1 small nuclear ribonucleoprotein particle. In this narrative review, we summarise the results of a systematic literature research which was performed as part of the European Reference Network on Rare and Complex Connective Tissue and Musculoskeletal Diseases project, aimed at evaluating existing clinical practice guidelines (CPGs) or recommendations. Since no specific CPGs on MCTD were found, other CPGs developed for other CTDs were taken into consideration in order to discuss what can be applied to MCTD even if designed for other diseases. Three major objectives were proposed for the future development of CPGs: MCTD diagnosis (diagnostic criteria), MCTD initial and follow-up evaluations, MCTD treatment. Early diagnosis, epidemiological data, assessment of burden of disease and QOL aspects are among the unmet needs identified by patients.pt_PT
dc.description.sponsorshipThis publication was funded by the European Union’s Health Programme (2014-2020)pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRMD Open. 2018 Oct 18;4(Suppl 1):e000783.pt_PT
dc.identifier.doi10.1136/rmdopen-2018-000783pt_PT
dc.identifier.eissn2056-5933
dc.identifier.urihttp://hdl.handle.net/10451/46799
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBMJ Publishing Group, Ltd.pt_PT
dc.relation.publisherversionhttps://rmdopen.bmj.com/pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectMixed connective tissue diseasept_PT
dc.subjectEuropean reference networkspt_PT
dc.subjectERN reconnetpt_PT
dc.subjectClinical practice guidelinespt_PT
dc.subjectUnmet needspt_PT
dc.titleMixed connective tissue disease : state of the art on clinical practice guidelinespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issueSuppl 1pt_PT
oaire.citation.titleRMD Openpt_PT
oaire.citation.volume4pt_PT
person.familyNameFonseca
person.givenNameJoão
person.identifier.ciencia-idF310-B85D-57C7
person.identifier.orcid0000-0003-1432-3671
person.identifier.scopus-author-id7101983519
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication1772dc12-7c55-4c76-ae2d-c23270172480
relation.isAuthorOfPublication.latestForDiscovery1772dc12-7c55-4c76-ae2d-c23270172480

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