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Prognostic factors after liver resection for colorectal liver metastasis

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dc.contributor.authorMatias, Margarida
dc.contributor.authorCasa-Nova, Mafalda
dc.contributor.authorFaria, Mariana
dc.contributor.authorPires, Ricardo
dc.contributor.authorTato-Costa, Joana
dc.contributor.authorRibeiro, Maria Leonor
dc.contributor.authorCosta, Luis
dc.date.accessioned2022-09-29T16:12:56Z
dc.date.available2022-09-29T16:12:56Z
dc.date.issued2015
dc.description© Ordem dos Médicos 2015pt_PT
dc.description.abstractIntroduction: Surgery is the only potentially curative treatment for patients with colorectal liver metastases, resulting in 5-year survival rates of 36 - 58. Although many studies have been performed to determine prognostic factors for tumor recurrence and survival after resection of colorectal liver metastases, there are few prognostic scoring systems stratifying patients undergoing surgery for colorectal liver metastases into risk group models. Objectives: To identify, evaluate and compare the existing prognostic scores for survival after surgery for resection of colorectal liver metastases. Material and methods: Electronic search in PubMed, Cochrane and Embase from 1990 to 2013 using the terms ' hepatic resection', ' colorectal cancer' , 'liver metastasis', ' hepatectomy', ' prognostic' , and ' score' . Only studies proposing a prognostic model or risk stratification based on clinical and/or pathological variables were included. Results: From 1996 to June 2013, 19 scoring systems were identified, including one nomogram. Thirty prognostic factors were identified although none of the factors was common to all prognostic models. The 4 factors most often included were: number of liver metastases, regional lymph node metastization of primary tumor, preoperative CEA level and maximum size of metastases. The median study sample size was 305 patients (81-1 568 patients) and median follow-up was 33 months (16-54 months). All studies were retrospective and used the Cox proportional hazards model for multi-variable analysis. Conclusion: Several factors have been constantly reported as having prognostic value after liver resection of colorectal livermetastases, although there is no consensus on the ideal scoring system.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationActa Med Port. 2015 May-Jun;28(3):357-369pt_PT
dc.identifier.doi10.20344/amp.4816pt_PT
dc.identifier.eissn1646-0758
dc.identifier.issn0870-399X
dc.identifier.urihttp://hdl.handle.net/10451/54636
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherOrdem dos Médicospt_PT
dc.relation.publisherversionhttps://actamedicaportuguesa.com/revista/index.php/amp/indexpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectColorectal Neoplasmspt_PT
dc.subjectHepatectomypt_PT
dc.subjectLiver neoplasms/secondarypt_PT
dc.subjectLiver neoplasms/surgerypt_PT
dc.subjectPrognosispt_PT
dc.titlePrognostic factors after liver resection for colorectal liver metastasispt_PT
dc.title.alternativeFactores de prognóstico após ressecção de metástases hepáticas de cancro colo-rectalpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage369pt_PT
oaire.citation.issue3pt_PT
oaire.citation.startPage357pt_PT
oaire.citation.titleActa Médica Portuguesapt_PT
oaire.citation.volume28pt_PT
person.familyNameMatias
person.familyNameRibeiro
person.familyNameCosta
person.givenNameMargarida
person.givenNameMaria Leonor
person.givenNameLuis
person.identifier.ciencia-id041E-4ADE-FB64
person.identifier.orcid0000-0002-3088-9029
person.identifier.orcid0000-0002-7657-0902
person.identifier.orcid0000-0002-4782-7318
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationfcc849dc-768a-4a55-924c-67eab2903027
relation.isAuthorOfPublication89129795-057a-43b2-8f45-acbbc4ec0eb4
relation.isAuthorOfPublication8a2ab4c6-ba86-4433-b4b7-6256d81890e5
relation.isAuthorOfPublication.latestForDiscovery8a2ab4c6-ba86-4433-b4b7-6256d81890e5

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