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Prevention of nausea and vomiting in patients undergoing oral anticancer therapies for solid tumors

2015Artigo científico Acesso aberto
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dc.contributor.authorCosta, Ana Lúcia
dc.contributor.authorMarques, Catarina
dc.contributor.authorPacheco, Teresa
dc.contributor.authorMacedo, Daniela
dc.contributor.authorSousa, Ana Rita
dc.contributor.authorPulido, Catarina
dc.contributor.authorQuintela, António
dc.contributor.authorCosta, Luis
dc.date.accessioned2022-03-15T17:15:21Z
dc.date.available2022-03-15T17:15:21Z
dc.date.issued2015
dc.descriptionCopyright © 2015 Ana Lúcia Costa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.pt_PT
dc.description.abstractChemotherapy-induced nausea and vomiting (CINV) is still a common and debilitating side effect despite recent advances in its prevention and treatment. The intrinsic emetogenicity of chemotherapy agents allowed grouping into four risk groups (high, moderate, low, and minimal risk of emetogenicity). The prevention of acute and delayed CINV for intravenous agents and one day regimens is well studied, although, there are few data about management of CINV induced by oral cytotoxic agents and targeted therapies, usually administered in extended regimens of daily oral use. Until now treatment of nausea and vomiting caused by oral antineoplastic agents remains largely empirical. The level of evidence of prophylactic antiemetics recommended for these agents is low. There are differences in the classification of emetogenic potential of oral antineoplastic agents between the international guidelines and different recommendations for prophylactic antiemetic regimens. Herein we review the evidence for antiemetic regimens for the most used oral antineoplastic agents for solid tumors and propose antiemetic regimens for high to moderate risk and low to minimal risk of emetogenicity.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBiomed Res Int. 2015;2015:309601pt_PT
dc.identifier.doi10.1155/2015/309601pt_PT
dc.identifier.eissn2314-6141
dc.identifier.issn2314-6133
dc.identifier.urihttp://hdl.handle.net/10451/51762
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherHidawipt_PT
dc.relation.publisherversionhttps://www.hindawi.com/journals/bmri/pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.titlePrevention of nausea and vomiting in patients undergoing oral anticancer therapies for solid tumorspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage7pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleBioMed Research Internationalpt_PT
person.familyNameMarques
person.familyNamePacheco
person.familyNameMacedo
person.familyNameCosta
person.givenNameCatarina
person.givenNameTeresa
person.givenNameDaniela
person.givenNameLuis
person.identifier.ciencia-idB311-6AE6-9A83
person.identifier.ciencia-idAE1D-0F79-3B24
person.identifier.ciencia-id041E-4ADE-FB64
person.identifier.orcid0000-0003-3558-3966
person.identifier.orcid0000-0002-5506-0233
person.identifier.orcid0000-0002-9681-1224
person.identifier.orcid0000-0002-4782-7318
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication02a5a89e-8c42-48b2-a57d-3dc22e046324
relation.isAuthorOfPublication45c53fd3-4da2-4d58-8c15-b13968b8689d
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relation.isAuthorOfPublication8a2ab4c6-ba86-4433-b4b7-6256d81890e5
relation.isAuthorOfPublication.latestForDiscovery8a2ab4c6-ba86-4433-b4b7-6256d81890e5

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