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Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants

2022Journal article Open access
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dc.contributor.authorEssoh, Anyse P.
dc.contributor.authorLiberal, Ângela
dc.contributor.authorFernandes, Ângela
dc.contributor.authorDias, Maria Inês
dc.contributor.authorPereira, Carla
dc.contributor.authorMandim, Filipa
dc.contributor.authorMoldão, Margarida
dc.contributor.authorCravo, Pedro
dc.contributor.authorDuarte, Maria Paula
dc.contributor.authorMoura, Mónica
dc.contributor.authorRomeiras, Maria M.
dc.contributor.authorBarros, Lillian
dc.date.accessioned2022-10-20T14:32:13Z
dc.date.available2022-10-20T14:32:13Z
dc.date.issued2022
dc.description.abstractThe use of medicinal plants in a variety of health conditions remains essential for the discovery of new treatments. The present study aimed to investigate the bioactive properties of three native plants from Cabo Verde Islands, namely Artemisia gorgonum Webb, Sideroxylon marginatum (Decne. ex Webb) Cout., and Tamarix senegalensis DC., contributing to the characterization of lessknown medicinal plants and their potential benefits for human health. Known compounds, such as kaempferol, quercetin, caffeyolquinic, and apigenin derivatives, among others, were detected in the plant species under study. Overall, all species demonstrated good antioxidant capacity, especially the ethanolic extracts of A. gorgonum (EC50 = 0.149 mg/mL) in TBARS assay. Moreover, the ethanolic extracts of the studied plants showed cytotoxic properties against tumor cells, and again the A. gorgonum extract proved to be the most effective in inhibiting tumor growth, mainly in the CaCO2 (GI50 = 17.3 g/mL) and AGS (GI50 = 18.2 g/mL) cell lines. Only the ethanolic extracts of T. senegalensis and S. marginatum demonstrated anti-inflammatory activity, albeit weak (EC50 = 35 and 43 g/mL, respectively). The present study contributed to increased knowledge about the bioactive properties of these plants commonly used in traditional medicine, some of which was discussed for the first time, opening new perspectives for their use in a wider range of health conditions, especially in African countries, where access to modern health care is more limitedpt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationP. Essoh, A.; Liberal, Â.; Fernandes, Â.; Dias, M.I.; Pereira, C.; Mandim, F.; Moldão-Martins, M.; Cravo, P.; Duarte, M.P.; Moura, M.; et al. Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants. Pharmaceuticals 2022, 15, 1162pt_PT
dc.identifier.doihttps://doi.org/10.3390/ ph15091162pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.5/25760
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationCVAgrobiodiversity/333111699pt_PT
dc.relationMountain Research Center
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectbioactive propertiespt_PT
dc.subjectCabo Verdept_PT
dc.subjectendemic medicinal plantspt_PT
dc.subjecttraditional medicinept_PT
dc.titleEvaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plantspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleMountain Research Center
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00690%2F2020/PT
oaire.citation.titlePharmaceuticalspt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameMoldao-Martins
person.familyNameRomeiras
person.givenNameMargarida
person.givenNameMaria
person.identifier520836
person.identifier.ciencia-id9F1F-85B6-C3EC
person.identifier.ciencia-id6A1C-085E-9038
person.identifier.orcid0000-0003-0558-8715
person.identifier.orcid0000-0002-9373-6302
person.identifier.ridJ-4552-2013
person.identifier.scopus-author-id6506047512
person.identifier.scopus-author-id15842082800
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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relation.isAuthorOfPublicationa66d151c-8bfa-4f32-ba8e-b20f9870ba24
relation.isAuthorOfPublication.latestForDiscoverya66d151c-8bfa-4f32-ba8e-b20f9870ba24
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