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The treatment of liver metastases in patients with neuroendocrine tumors in 2012

2013Artigo científico Acesso aberto
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dc.contributor.authorMacedo, Daniela
dc.contributor.authorAmaral, Teresa
dc.contributor.authorFernandes, Isabel
dc.contributor.authorSousa, Ana Rita
dc.contributor.authorCosta, Ana Lúcia
dc.contributor.authorTávora, Isabel
dc.contributor.authorQuintela, António
dc.contributor.authorCortes, Paulo
dc.contributor.authorCosta, Luis
dc.date.accessioned2021-12-15T15:28:59Z
dc.date.available2021-12-15T15:28:59Z
dc.date.issued2013
dc.descriptionCopyright © 2013 Daniela Macedo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.pt_PT
dc.description.abstractNeuroendocrine tumors (NETs) comprise a heterogeneous group of tumors that form a distinct entity. Approximately 75-80% of patients present with liver metastases at the time of their diagnosis, and 20%-25% will develop these lesions in the course of their disease. The presence of secondary deposits in the liver significantly increases the morbidity and mortality in these patients. The only potentially curative treatment is the surgical resection of the primary tumor and hepatic lesions. However, only 10% of patients presents under ideal conditions for that approach. Several techniques aimed at localized liver lesions have been applied also with interesting results in terms of survival and symptom control. The same has been demonstrated with new systemic therapies (target therapies). However, these are still under study, in order to define their true role in the management of these patients. This paper intends to address, in a general way, the various treatment options in patients with liver metastases from neuroendocrine tumors.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationISRN hepatology, 2013, 702167pt_PT
dc.identifier.doi10.1155/2013/702167pt_PT
dc.identifier.eissn2314-4041
dc.identifier.urihttp://hdl.handle.net/10451/50422
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherHindawipt_PT
dc.relation.publisherversionhttps://www.hindawi.com/journals/isrn/pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.titleThe treatment of liver metastases in patients with neuroendocrine tumors in 2012pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage9pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleISRN Hepatologypt_PT
oaire.citation.volume2013pt_PT
person.familyNameMacedo
person.familyNameFernandes
person.familyNameCosta
person.givenNameDaniela
person.givenNameIsabel
person.givenNameLuis
person.identifier.ciencia-idAE1D-0F79-3B24
person.identifier.ciencia-idD811-E1C9-9209
person.identifier.ciencia-id041E-4ADE-FB64
person.identifier.orcid0000-0002-9681-1224
person.identifier.orcid0000-0003-4032-7713
person.identifier.orcid0000-0002-4782-7318
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationbf82b11c-67d5-47a9-9516-dd1875cebe29
relation.isAuthorOfPublication65582123-edcc-4bda-a6a0-74916b61d540
relation.isAuthorOfPublication8a2ab4c6-ba86-4433-b4b7-6256d81890e5
relation.isAuthorOfPublication.latestForDiscoverybf82b11c-67d5-47a9-9516-dd1875cebe29

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