Publication
Efficient synthesis of spiroisoxazoline oxindoles
| dc.contributor.author | Ribeiro, Carlos J. A. | |
| dc.contributor.author | Kumar, S. Praveen | |
| dc.contributor.author | Moreira, Rui | |
| dc.contributor.author | Santos, Maria M. M. | |
| dc.date.accessioned | 2013-04-02T13:51:01Z | |
| dc.date.available | 2013-04-02T13:51:01Z | |
| dc.date.issued | 2012 | |
| dc.description | Acknowledgments: We thank Fundação para a Ciência e Tecnologia (Portugal) for financial support [Projects PTDC/QUI-QUI/111664/2009 and PTDC/SAU-FAR/110848/2009 and Fellowships SFRH/BD/69258/2010 and SFRH/BPD/44481/2008]. | por |
| dc.description.abstract | The synthesis of spiroisoxazoline oxindoles containing ester groups at position 4′ and aromatic or ester groups at position 3′ of the isoxazoline ring is reported. The compounds were synthesized in yields up to 94% by 1,3-dipolar cycloaddition of 3-methylene indolin-2-ones and chlorooximes in the presence of triethylamine or zinc. | por |
| dc.description.sponsorship | Fundação para a Ciência e Tecnologia (Portugal) | por |
| dc.identifier.citation | Tetrahedron Letters 53 (2012) 281–284 | por |
| dc.identifier.issn | 0040-4039 | |
| dc.identifier.uri | http://dx.doi.org/10.1016/j.tetlet.2011.10.139 | |
| dc.identifier.uri | http://www.sciencedirect.com/science/article/pii/S0040403911018934 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.relation | Enantioselective synthesis of indole alkaloids and their application as NMDA antagonists | |
| dc.relation.publisherversion | http://dx.doi.org/10.1016/j.tetlet.2011.10.139 | por |
| dc.subject | Spirooxindole | por |
| dc.subject | Isoxazoline | por |
| dc.subject | 1,3-Dipolar cycloaddition | por |
| dc.subject | Chlorooxime | por |
| dc.subject | Zinc | por |
| dc.title | Efficient synthesis of spiroisoxazoline oxindoles | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.awardTitle | Enantioselective synthesis of indole alkaloids and their application as NMDA antagonists | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FQUI-QUI%2F111664%2F2009/PT | |
| oaire.citation.endPage | 284 | por |
| oaire.citation.startPage | 281 | por |
| oaire.citation.title | Tetrahedron Letters | por |
| oaire.citation.volume | 53 | por |
| oaire.fundingStream | 3599-PPCDT | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | restrictedAccess | por |
| rcaap.type | article | por |
| relation.isProjectOfPublication | 07316c55-1daa-4b66-aa2f-3077d53d7cda | |
| relation.isProjectOfPublication.latestForDiscovery | 07316c55-1daa-4b66-aa2f-3077d53d7cda |