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Supra-normal left ventricular function

dc.contributor.authorOno, Ryohei
dc.contributor.authorMenezes Falcão, Luiz
dc.date.accessioned2023-09-29T15:16:44Z
dc.date.available2023-09-29T15:16:44Z
dc.date.issued2023
dc.description© 2023 Elsevier Inc. All rights reserved.pt_PT
dc.description.abstractHeart failure (HF) is often categorized by left ventricular (LV) ejection fraction (LVEF). A new category of HF characterized by supra-normal LVEF (>65%), named HF with supra-normal ejection fraction (HFsnEF), has been recently proposed. Some studies reported that patients with supra-normal LVEF might have an increased risk of long-term major adverse cardiovascular events and U-shaped mortality patterns. Currently, the prognosis of HFsnEF is not well established but seems to be associated with an increased risk of long-term major adverse cardiovascular events. It has been reported that HFsnEF is more prevalent in women and is associated with higher prevalence of nonischemic HF, higher blood urea nitrogen plasma levels, lower levels of natriuretic peptides, and to be less likely treated with β blockers. The pathophysiology of HFsnEF would be associated with microvascular dysfunction because of microvascular inflammation or reduced coronary flow reserve, and low stroke volume index with smaller cardiac chamber dimensions and concentric LV geometry. In this study, we systematically reviewed published data on patients with s supra-normal LV function and reported its definition, proposed pathophysiology, phenotypes, diagnostic strategy, and prognosis.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationAm J Cardiol. 2023 Sep 19;207:84-92pt_PT
dc.identifier.doi10.1016/j.amjcard.2023.08.169pt_PT
dc.identifier.eissn1879-1913
dc.identifier.issn0002-9149
dc.identifier.urihttp://hdl.handle.net/10451/59513
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/journal/the-american-journal-of-cardiologypt_PT
dc.subjectHFpEFpt_PT
dc.subjectHeart failurept_PT
dc.subjectLeft ventricular ejection fractionpt_PT
dc.subjectSupra-normalpt_PT
dc.titleSupra-normal left ventricular functionpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage92pt_PT
oaire.citation.startPage84pt_PT
oaire.citation.titleThe American Journal of Cardiologypt_PT
oaire.citation.volume207pt_PT
person.familyNameMenezes Falcão
person.givenNameLuiz
person.identifier.ciencia-id0313-9D22-D93B
person.identifier.orcid0000-0003-3574-9807
person.identifier.ridF-1958-2017
person.identifier.scopus-author-id6505933124
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication9bc1a5a7-651a-4ed6-82d4-0d3c607850c6
relation.isAuthorOfPublication.latestForDiscovery9bc1a5a7-651a-4ed6-82d4-0d3c607850c6

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