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Avaliação da qualidade de vida em doentes com metástases ósseas submetidos a radioterapia
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Resumo(s)
INTRODUÇÃO: A avaliação da qualidade de vida (QdV) nos doentes com metástases ósseas (MO) tem vindo a ser reconhecida como um importante objetivo complementar da terapêutica oncológica. O objetivo principal deste estudo foi avaliar a evolução da QdV nestes doentes, antes e após o tratamento de radioterapia.
MATERIAL E MÉTODOS: Foram incluídos 41 doentes com diagnóstico de MO e proposta de radioterapia no Centro Clínico Champalimaud (CCC), de Fevereiro a Novembro de 2017. Foram aplicados os questionários da European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 e QLQ-BM22 antes do tratamento (T0), uma semana depois (T1) e um mês depois (T2) do final da radioterapia.
RESULTADOS: Quarenta doentes completaram o preenchimento dos questionários nos três tempos propostos, 28 do sexo feminino e 12 do sexo masculino, com uma média de idades de 61,4 anos. Os resultados reportam diferenças estatisticamente significativas nos seguintes parâmetros: QdV global, role functioning, função emocional, fadiga, dor, dispneia, locais de dor, características da dor e interferência funcional, sendo que, em todos eles se verificou um aumento da QdV ao longo do tempo. Não foram observadas alterações significativas quanto à influência do número de sessões ou de lesões na QdV dos doentes.
CONCLUSÕES: Os resultados obtidos permitem concluir que se verifica uma melhoria da QdV dos doentes com MO, submetidos a radioterapia, ao longo do tempo. À semelhança do que a literatura preconiza, não se observam diferenças significativas entre os doentes que realizaram sessão única ou várias sessões.
BACKGROUND: The assessment of the Quality of Life (QoL) in patients with bone metastases has been increasingly recognized as an important outcome in Oncology. The main purpose of this study was to evaluate the QoL in these patients, before and after radiotherapy treatment. MATERIALS AND METHODS: 41 patients diagnosed with bone metastases and refered for radiotherapy at the CCC between February and November of 2017 were included in the study. The QLQ-C30 and QLQ -BM22 European Organization for Research and Treatment of Cancer (EORTC) questionnaires were applied before the treatment (T0) and one week (T1) and one month after (T2) the end of radiotherapy. RESULTS: Forty patients completed all 3 questionnaires at determined time point - 28 females, 12 males, mean age of 61.4 years. The results report statistically significant differences in the following parameters: global QoL, functional function, emotional function, fatigue, pain, dyspnea, pain sites, pain characteristics and functional interference, with an increase of the QoL in all of them over time. No significant new findings were observed for the influence of the number of sessions or lesions in the QoL of the patients. CONCLUSIONS: The results obtained allow us to conclude that there is an improvement over time in bone metastases patients QoL, submitted to radiotherapy. As reported in the literature, there is no significant difference between patients submitted to one treatment session or more than one treatment sessions.
BACKGROUND: The assessment of the Quality of Life (QoL) in patients with bone metastases has been increasingly recognized as an important outcome in Oncology. The main purpose of this study was to evaluate the QoL in these patients, before and after radiotherapy treatment. MATERIALS AND METHODS: 41 patients diagnosed with bone metastases and refered for radiotherapy at the CCC between February and November of 2017 were included in the study. The QLQ-C30 and QLQ -BM22 European Organization for Research and Treatment of Cancer (EORTC) questionnaires were applied before the treatment (T0) and one week (T1) and one month after (T2) the end of radiotherapy. RESULTS: Forty patients completed all 3 questionnaires at determined time point - 28 females, 12 males, mean age of 61.4 years. The results report statistically significant differences in the following parameters: global QoL, functional function, emotional function, fatigue, pain, dyspnea, pain sites, pain characteristics and functional interference, with an increase of the QoL in all of them over time. No significant new findings were observed for the influence of the number of sessions or lesions in the QoL of the patients. CONCLUSIONS: The results obtained allow us to conclude that there is an improvement over time in bone metastases patients QoL, submitted to radiotherapy. As reported in the literature, there is no significant difference between patients submitted to one treatment session or more than one treatment sessions.
Descrição
Tese de mestrado, Cuidados Paliativos, Universidade de Lisboa, Faculdade de Medicina, 2018
Palavras-chave
Qualidade de vida Metástases ósseas Radioterapia Teses de mestrado - 2018