Repository logo
 
Publication

Molecular epidemiology, virulence traits and antimicrobial resistance signatures of Aeromonas spp. in the critically endangered iberochondrostoma iusitanicum follow geographical and seasonal patterns

2021-06-22Journal article Open access
Simple item page
dc.contributor.authorGrilo, Miguel
dc.contributor.authorIsidoro, Sara
dc.contributor.authorChambel, Lélia
dc.contributor.authorMarques, Carolina S.
dc.contributor.authorMarques, Tiago A.
dc.contributor.authorSousa-Santos, C.
dc.contributor.authorRobalo, Joana
dc.contributor.authorOliveira, Manuela
dc.date.accessioned2021-11-05T17:50:30Z
dc.date.available2021-11-05T17:50:30Z
dc.date.issued2021-06-22
dc.descriptionResearch Areas: Infectious Diseases ; Pharmacology & Pharmacypt_PT
dc.description.abstractDespite the fact that freshwater fish populations are experiencing severe declines worldwide, our knowledge on the interaction between endangered populations and pathogenic agents remains scarce. In this study, we investigated the prevalence and structure of Aeromonas communities isolated from the critically endangered Iberochondrostoma lusitanicum, a model species for threatened Iberian leuciscids, as well as health parameters in this species. Additionally, we evaluated the virulence profiles, antimicrobial resistance signatures and genomic relationships of the Aeromonas isolates. Lesion prevalence, extension and body condition were deeply affected by location and seasonality, with poorer performances in the dry season. Aeromonas composition shifted among seasons and was also different across river streams. The pathogenic potential of the isolates significantly increased during the dry season. Additionally, isolates displaying clinically relevant antimicrobial resistance phenotypes (carbapenem and fluroquinolone resistance) were detected. As it inhabits intermittent rivers, often reduced to disconnected pools during the summer, the dry season is a critical period for I. lusitanicum, with lower general health status and a higher potential of infection by Aeromonas spp. Habitat quality seems a determining factor on the sustainable development of this fish species. Also, these individuals act as reservoirs of important antimicrobial resistant bacteria with potential implications for public health.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationGrilo ML, Isidoro S, Chambel L, Marques CS, Marques TA, Sousa-Santos C, Robalo JI, Oliveira M. 2021. Molecular epidemiology, virulence traits and antimicrobial resistance signatures of Aeromonas spp. in the critically endangered iberochondrostoma iusitanicum follow geographical and seasonal patterns. Antibiotics, 10(7):759. DOI:10.3390/antibiotics10070759pt_PT
dc.identifier.doi10.3390/antibiotics10070759pt_PT
dc.identifier.issn2079-6382
dc.identifier.urihttp://hdl.handle.net/10400.5/22518
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationMARE/UIDB/MAR/04292/2020pt_PT
dc.relationMARE/UIDP/MAR/04292/2020pt_PT
dc.relationC10571Kpt_PT
dc.relation.publisherversionhttps://www.mdpi.com/2079-6382/10/7/759pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectAeromonaspt_PT
dc.subjectAntimicrobial resistancept_PT
dc.subjectVirulencept_PT
dc.subjectTypingpt_PT
dc.subjectLeuciscidpt_PT
dc.subjectFishpt_PT
dc.titleMolecular epidemiology, virulence traits and antimicrobial resistance signatures of Aeromonas spp. in the critically endangered iberochondrostoma iusitanicum follow geographical and seasonal patternspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/157379/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/157257/PT
oaire.citation.conferencePlaceBasel, SWITZERLANDpt_PT
oaire.citation.issue759pt_PT
oaire.citation.titleAntibioticspt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
person.familyNameGrilo
person.familyNameMarcão Chambel
person.familyNameSegurado Marques
person.familyNameMarques
person.familyNameSousa-Santos
person.familyNameRobalo
person.familyNameOliveira
person.givenNameMiguel
person.givenNameLélia Mariana
person.givenNameCarolina
person.givenNameTiago A.
person.givenNameCarla
person.givenNameJoana
person.givenNameManuela
person.identifiersY7IRmQAAAAJ
person.identifier403787
person.identifier.ciencia-id4B17-DF6F-1A51
person.identifier.ciencia-id7D11-AAC8-1F50
person.identifier.ciencia-id5A1D-289B-F352
person.identifier.ciencia-id161F-0DDB-81E2
person.identifier.ciencia-id1111-711D-31B2
person.identifier.ciencia-idD211-4FAD-537A
person.identifier.ciencia-idBE1E-2B3B-92D2
person.identifier.orcid0000-0001-7364-821X
person.identifier.orcid0000-0002-1672-1473
person.identifier.orcid0000-0002-5936-9342
person.identifier.orcid0000-0002-2581-1972
person.identifier.orcid0000-0002-4513-5553
person.identifier.orcid0000-0002-7470-0574
person.identifier.orcid0000-0002-3910-1525
person.identifier.ridB-5385-2012
person.identifier.ridN-9960-2014
person.identifier.scopus-author-id57195729611
person.identifier.scopus-author-id6503947335
person.identifier.scopus-author-id6603703024
person.identifier.scopus-author-id12769973800
person.identifier.scopus-author-id6506759340
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication1f136cc1-1f56-40b3-971b-aab3edaa7cab
relation.isAuthorOfPublication70ea7a73-3e04-4cc2-aef5-f258ce5e06de
relation.isAuthorOfPublication8e2b3dc3-637b-447e-b83b-c73b220b2941
relation.isAuthorOfPublication5473ec39-dad8-4a3d-a2d7-6dd2b05ce36f
relation.isAuthorOfPublicationbe9746c6-b869-4104-ac52-61be82b3f9e6
relation.isAuthorOfPublication76cdab17-838a-44f1-bfd6-cc16620564ad
relation.isAuthorOfPublicationabd012d1-0b2c-43f6-ba34-5f65c785a479
relation.isAuthorOfPublication.latestForDiscovery1f136cc1-1f56-40b3-971b-aab3edaa7cab
relation.isProjectOfPublicationa07fd1c0-e6df-4f42-8ff8-d4cc2a1c95ed
relation.isProjectOfPublication080f84e4-1b76-4cb9-842c-32792da3367b
relation.isProjectOfPublication.latestForDiscoverya07fd1c0-e6df-4f42-8ff8-d4cc2a1c95ed

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Molecular epidemiology, virulence traits and antimicrobial resistance signatures of Aeromonas spp. in the critically endangered iberochondrostoma iusitanicum follow geographical and seasonal patterns.PDF
Size:
2.07 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

CIISA - Artigos em revistas internacionais