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A tailored approach for appendicular impending and pathologic fractures in solid cancer metastases

2022Journal article Open access
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dc.contributor.authorSoares Do Brito, Joaquim
dc.contributor.authorBrás, Raquel
dc.contributor.authorAbrunhosa-Branquinho, André
dc.contributor.authorFernandes, Isabel
dc.contributor.authorFernandes Gomes, Inês
dc.contributor.authorCasimiro, Sandra
dc.contributor.authorCosta, Luis
dc.date.accessioned2022-09-23T14:36:06Z
dc.date.available2022-09-23T14:36:06Z
dc.date.issued2022
dc.description© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).pt_PT
dc.description.abstractAdvances in medical and surgical treatment have played a major role in increasing the survival rates of cancer patients with metastatic bone disease. The clinical course of patients with bone metastases is often impaired by bone complications, such as bone fractures, which have a substantial negative impact on clinical outcomes. To optimize clinical results and prevent a detrimental impact on patients' health, a tailored approach should be defined for any given patient. The optimal management of impending or pathologic fractures is unknown and relies on a multidisciplinary approach to tailor clinical decisions to each individual patient. The ability to control systemic disease, the extent, location and nature of bone metastases, and the biology of the underlying tumor, are the main factors that will define the strategy to follow. The present review covers the most recent data regarding impending and pathologic fractures in patients with bone metastases, and discusses the medical and surgical management of patients presenting with metastatic bone disease in different clinical settings.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCancers (Basel). 2022 Feb 11;14(4):893pt_PT
dc.identifier.doi10.3390/cancers14040893pt_PT
dc.identifier.eissn2072-6694
dc.identifier.urihttp://hdl.handle.net/10451/54575
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relation.publisherversionhttps://www.mdpi.com/journal/cancerspt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectBone metastasespt_PT
dc.subjectClinical managementpt_PT
dc.subjectImpending fracturept_PT
dc.subjectPathologic fracturept_PT
dc.subjectTailored approachpt_PT
dc.titleA tailored approach for appendicular impending and pathologic fractures in solid cancer metastasespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue4pt_PT
oaire.citation.titleCancerspt_PT
oaire.citation.volume14pt_PT
person.familyNameSoares do Brito
person.familyNameLopes Brás
person.familyNameAbrunhosa-Branquinho
person.familyNameFernandes
person.familyNameFernandes Gomes
person.familyNameCara de Anjo Casimiro
person.familyNameCosta
person.givenNameJoaquim
person.givenNameRaquel
person.givenNameAndré
person.givenNameIsabel
person.givenNameInês
person.givenNameSandra Cristina
person.givenNameLuis
person.identifier.ciencia-id7B10-E6A8-C67E
person.identifier.ciencia-idD811-E1C9-9209
person.identifier.ciencia-id4114-34EA-AD95
person.identifier.ciencia-id0F12-5181-0B22
person.identifier.ciencia-id041E-4ADE-FB64
person.identifier.orcid0000-0003-0132-7526
person.identifier.orcid0000-0001-5150-9235
person.identifier.orcid0000-0001-8432-0324
person.identifier.orcid0000-0003-4032-7713
person.identifier.orcid0000-0003-0985-0821
person.identifier.orcid0000-0002-6917-4477
person.identifier.orcid0000-0002-4782-7318
person.identifier.scopus-author-id55846539900
person.identifier.scopus-author-id14043403400
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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relation.isAuthorOfPublication.latestForDiscovery512a88ea-ebfa-4691-a024-43716648abb8

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