Logo do repositório
 
Publicação

Physical activity in vascular cognitive impairment: systematic review with meta-analysis

2023Artigo científico Acesso restrito
Ver registo simples
dc.contributor.authorVítor, Joana
dc.contributor.authorMelita, Catarina
dc.contributor.authorRodrigues, Mário
dc.contributor.authorde Sousa, Diana Aguiar
dc.contributor.authorCosta, João
dc.contributor.authorFerro, José
dc.contributor.authorVerdelho, Ana
dc.date.accessioned2023-05-23T10:53:46Z
dc.date.available2023-05-23T10:53:46Z
dc.date.issued2023
dc.description© 2023 Elsevier Inc. All rights reserved.pt_PT
dc.description.abstractBackground: Vascular cognitive impairment (VCI) is the second most common cause of cognitive impairment worldwide and includes a spectrum from vascular cognitive impairment no dementia (VCIND) to vascular dementia (VaD). There is no specific pharmacological treatment approved for VCI. Physical activity has been indicated to be a promising preventive measure for cognition, with direct as indirectly benefits, while improving several modifiable vascular risk factors, so potentially effective when considering VCI. Our aim was to conduct a systematic review with a meta-analysis approaching the potential preventive role of physical activity on VCI. Methods: A systematic search was conducted in 7 databases. A total of 6786 studies were screened and assessed for eligibility, culminating in the inclusion of 9 observational prospective studies assessing physical activity impact irrespectively the type for quality assessment and qualitative and quantitative synthesis. Quantitative synthesis was performed using the reported adjusted HRs. Physical activity was handled as a dichotomous variable, with two groups created (high versus low physical activity). Subgroup analyses were done for risk of bias, VaD and length of follow-up. Results: There was considerable methodological heterogeneity across studies. Only three studies reported significant associations. The overall effect was statistically significant (HR 0.68, 95%CI 0.54-0.86, I2 6.8%), with higher levels of physical activity associated with a smaller risk of VCI overtime, particularly VaD. Conclusions: These findings suggest that physical activity is a potential preventive factor for vascular dementia. Insufficient data is available on VCIND. Randomized studies are desired to confirm these results.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationJ Stroke Cerebrovasc Dis. 2023 May 6;32(8):107133pt_PT
dc.identifier.doi10.1016/j.jstrokecerebrovasdis.2023.107133pt_PT
dc.identifier.eissn1532-8511
dc.identifier.issn1052-3057
dc.identifier.urihttp://hdl.handle.net/10451/57524
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/journal/journal-of-stroke-and-cerebrovascular-diseasespt_PT
dc.subjectPhysical activitypt_PT
dc.subjectPreventionpt_PT
dc.subjectSystematic reviewpt_PT
dc.subjectVascular cognitive impairmentpt_PT
dc.subjectVascular dementiapt_PT
dc.titlePhysical activity in vascular cognitive impairment: systematic review with meta-analysispt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue8pt_PT
oaire.citation.titleJournal of Stroke and Cerebrovascular Diseasespt_PT
oaire.citation.volume32pt_PT
person.familyNameRodrigues
person.familyNameAguiar de Sousa
person.familyNameCosta
person.familyNameMorão Cabral Ferro
person.familyNameVerdelho
person.givenNameMário
person.givenNameDiana
person.givenNameJoão
person.givenNameJosé Manuel
person.givenNameAna
person.identifier574112
person.identifier480560
person.identifier.ciencia-id571C-121A-5CCB
person.identifier.ciencia-id6F16-7E25-7AAF
person.identifier.ciencia-idFC14-938F-EBBD
person.identifier.orcid0000-0002-7310-755X
person.identifier.orcid0000-0002-6702-7924
person.identifier.orcid0000-0002-5831-4921
person.identifier.orcid0000-0002-2343-9097
person.identifier.orcid0000-0003-4945-4946
person.identifier.ridJ-4105-2013
person.identifier.scopus-author-id55781226000
person.identifier.scopus-author-id55499748300
person.identifier.scopus-author-id6602902026
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication020bbb76-0a2a-4d4f-acfa-56b813a41519
relation.isAuthorOfPublication1d984575-dd95-4ca1-9092-bf6f9914ba63
relation.isAuthorOfPublication0924f405-2d3a-4914-9097-24aa639bd97f
relation.isAuthorOfPublication9a568ce6-d218-44fc-982c-0ffe7bffc197
relation.isAuthorOfPublication11ec545d-3044-4ffd-b658-578d00f82d2a
relation.isAuthorOfPublication.latestForDiscovery9a568ce6-d218-44fc-982c-0ffe7bffc197

Ficheiros

Principais
A mostrar 1 - 1 de 1
Miniatura indisponível
Nome:
Physical_cognitive.pdf
Tamanho:
1008.58 KB
Formato:
Adobe Portable Document Format
Ver/Abrir
Licença
A mostrar 1 - 1 de 1
Miniatura indisponível
Nome:
license.txt
Tamanho:
1.2 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Ver/Abrir

Coleções

FM-ISAMB-Artigos em Revistas Internacionais
IMM - Artigos em Revistas Internacionais