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Impacto da oxigenoterapia hiperbárica na função erétil
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Orientador(es)
Resumo(s)
A disfunção erétil (DE) define-se como a incapacidade de obter e/ou manter uma ereção suficiente para um desempenho sexual satisfatório. A saúde sexual e a satisfação com a vida sexual são fatores importantes na qualidade de vida, pelo que esta entidade tem um impacto considerável na diminuição da mesma. Está demonstrado que a DE pode representar uma primeira manifestação de doença cardiovascular. O oxigénio hiperbárico (OHB), ao promover a oxigenação de tecidos e a angiogénese, pode mostrar-se eficaz na melhoria da função erétil, nomeadamente quando a causa subjacente da disfunção é vascular.
O objetivo deste trabalho foi avaliar o efeito da oxigenoterapia hiperbárica na função erétil. Para verificá-lo, realizou-se um estudo prospetivo e não interventivo, com recurso ao preenchimento do questionário International Index of Erectile Function (IIEF-5) e de um outro sobre comorbilidades e fatores de risco na consulta inicial e no final do tratamento.
Foram incluídos dezassete doentes, com diferentes níveis de disfunção erétil e avaliados parâmetros como o motivo de tratamento, o número de sessões de OHB a que foram submetidos, a idade e fatores de risco para disfunção erétil. Mais de metade dos doentes submetidos a OHB verificaram uma melhoria na sua função erétil, no final dos seus tratamentos. Foram, ainda, encontradas relações relevantes entre doentes com uma DE ligeira e melhoria da função erétil, e doentes submetidos a um menor número de sessões e melhoria da função erétil.
Como limitações identificadas, o preenchimento dos questionários pelos próprios doentes pode não ter sido feito de forma correta; alguns doentes, por terem diminuição da acuidade auditiva, não puderam ser contactados.
No futuro, seria importante a condução de um estudo com uma amostra de maiores dimensões, com uma avaliação padronizada, com o intuito de perceber qual o esquema terapêutico a aplicar nos doentes com DE.
Erectile dysfunction is defined as the inability to achieve and/or maintain an erection sufficient for satisfactory sexual performance. Sexual health and satisfaction with sexual life are important factors in quality of life, making this condition significantly impact its decrease. It has been shown that ED can be an initial manifestation of cardiovascular disease. Hyperbaric oxygen, by promoting tissue oxygenation and angiogenesis, can be effective in improving erectile function with, especially when the underlying cause of dysfunction is vascular. The objective of this study was to evaluate the effect of hyperbaric oxygen therapy on erectile function. To verify this, a prospective and non-interventional study was conducted, using the International Index of Erectile Function (IIEF-5) questionnaire and a questionnaire on comorbidities and risk factors at the initial consultation and at the end of treatment. Seventeen patients with varying levels of erectile dysfunction were included. Parameters evaluated included treatment rationale, number of hyperbaric oxygen therapy sessions undergone, age and risk factors for erectile dysfunction. More than half of the patients undergoing HBOT experienced improvement in their erectile function by the end of their treatments. Relevant outcomes were also found between patients with mild ED and improvement in erectile function, and patients who underwent a lower number of sessions and improvement in erectile function. Some identified limitations were that self-completion of the questionnaires by patients may not have been done correctly; some patients could not be contacted due to decreased hearing acuity. In the future, it would be important to conduct a study with a larger sample size and a standardized evaluation, in order to determine the therapeutic regimen to be applied to patients with ED.
Erectile dysfunction is defined as the inability to achieve and/or maintain an erection sufficient for satisfactory sexual performance. Sexual health and satisfaction with sexual life are important factors in quality of life, making this condition significantly impact its decrease. It has been shown that ED can be an initial manifestation of cardiovascular disease. Hyperbaric oxygen, by promoting tissue oxygenation and angiogenesis, can be effective in improving erectile function with, especially when the underlying cause of dysfunction is vascular. The objective of this study was to evaluate the effect of hyperbaric oxygen therapy on erectile function. To verify this, a prospective and non-interventional study was conducted, using the International Index of Erectile Function (IIEF-5) questionnaire and a questionnaire on comorbidities and risk factors at the initial consultation and at the end of treatment. Seventeen patients with varying levels of erectile dysfunction were included. Parameters evaluated included treatment rationale, number of hyperbaric oxygen therapy sessions undergone, age and risk factors for erectile dysfunction. More than half of the patients undergoing HBOT experienced improvement in their erectile function by the end of their treatments. Relevant outcomes were also found between patients with mild ED and improvement in erectile function, and patients who underwent a lower number of sessions and improvement in erectile function. Some identified limitations were that self-completion of the questionnaires by patients may not have been done correctly; some patients could not be contacted due to decreased hearing acuity. In the future, it would be important to conduct a study with a larger sample size and a standardized evaluation, in order to determine the therapeutic regimen to be applied to patients with ED.
Descrição
Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2024
Palavras-chave
Disfunção erétil Oxigenoterapia hiperbárica Urologia