Publication
Clinical presentation and management strategies of cardiovascular autonomic dysfunction following a COVID‐19 infection: a systematic review
| dc.contributor.author | Reis Carneiro, Diogo | |
| dc.contributor.author | Rocha, Isabel | |
| dc.contributor.author | Habek, Mario | |
| dc.contributor.author | Helbok, Raimund | |
| dc.contributor.author | Sellner, Johann | |
| dc.contributor.author | Struhal, Walter | |
| dc.contributor.author | Wenning, Gregor | |
| dc.contributor.author | Fanciulli, Alessandra | |
| dc.date.accessioned | 2023-02-10T12:28:10Z | |
| dc.date.available | 2023-02-10T12:28:10Z | |
| dc.date.issued | 2023 | |
| dc.description | © 2023 The Authors. European Journal of Neurology published by John Wiley & Sons Ltd on behalf of European Academy of Neurology. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. | pt_PT |
| dc.description.abstract | Background: Cardiovascular autonomic dysfunction may reportedly occur after a coronavirus-disease-2019 (COVID-19) infection, but the available evidence is scattered. Here we sought to understand the acute and mid-term effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on cardiovascular autonomic function. Methods: We performed a systematic PubMed, Embase, Web of Science, medRxiv, and bioRxiv search for cases of cardiovascular autonomic dysfunction during an acute SARS-CoV-2 infection or post-COVID-19 condition. The clinical-demographic characteristics of individuals in the acute versus post-COVID-19 phase were compared. Results: We screened 6470 titles and abstracts. Fifty-four full-length articles were included in the data synthesis. One-hundred and thirty-four cases were identified: 81 during the acute SARS-CoV-2 infection (24 thereof diagnosed by history) and 53 in the post-COVID-19 phase. Post-COVID-19 cases were younger than those with cardiovascular autonomic disturbances in the acute SARS-CoV-2 phase (42 vs. 51 years old, p = 0.002) and were more frequently women (68% vs. 49%, p = 0.034). Reflex syncope was the most common cardiovascular autonomic disorder in the acute phase (p = 0.008) and postural orthostatic tachycardia syndrome (POTS) the most frequent diagnosis in individuals with post-COVID-19 orthostatic complaints (p < 0.001). Full recovery was more frequent in individuals with acute versus post-COVID-19 onset of cardiovascular autonomic disturbances (43% vs. 15%, p = 0.002). Conclusions: There is evidence from the scientific literature about different types of cardiovascular autonomic dysfunction developing during and after COVID-19. More data about the prevalence of autonomic disorders associated with a SARS-CoV-2 infection are needed to quantify its impact on human health. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Eur J Neurol. 2023; 00: 1- 12 | pt_PT |
| dc.identifier.doi | 10.1111/ene.15714 | pt_PT |
| dc.identifier.eissn | 1468-1331 | |
| dc.identifier.issn | 1351-5101 | |
| dc.identifier.uri | http://hdl.handle.net/10451/56247 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Wiley | pt_PT |
| dc.relation.publisherversion | https://onlinelibrary.wiley.com/journal/14681331 | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt_PT |
| dc.subject | COVID-19 | pt_PT |
| dc.subject | Autonomic nervous system | pt_PT |
| dc.subject | Orthostatic hypotension | pt_PT |
| dc.subject | Postural orthostatic tachycardia syndrome | pt_PT |
| dc.subject | Syncope | pt_PT |
| dc.title | Clinical presentation and management strategies of cardiovascular autonomic dysfunction following a COVID‐19 infection: a systematic review | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.title | European Journal of Neurology | pt_PT |
| person.familyName | rocha | |
| person.givenName | isabel | |
| person.identifier.orcid | 0000-0002-7582-0893 | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
| relation.isAuthorOfPublication | 472714e8-fa6c-4d7b-9c4d-d6f5b55e39f4 | |
| relation.isAuthorOfPublication.latestForDiscovery | 472714e8-fa6c-4d7b-9c4d-d6f5b55e39f4 |