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The atrial fibrillation burden during the blanking period is predictive of time to recurrence after catheter ablation

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dc.contributor.authorCunha, Pedro
dc.contributor.authorPortugal, Guilherme
dc.contributor.authorLaranjo, Sérgio
dc.contributor.authorAlves, Marta
dc.contributor.authorLuísa Papoila, Ana
dc.contributor.authorValente, Bruno
dc.contributor.authorSofia Delgado, Ana
dc.contributor.authorLousinha, Ana
dc.contributor.authorPaulo, Margarida
dc.contributor.authorBrás, Manuel
dc.contributor.authorGuerra, Cátia
dc.contributor.authorCruz Ferreira, Rui
dc.contributor.authorOliveira, Mario
dc.date.accessioned2022-10-26T14:37:15Z
dc.date.available2022-10-26T14:37:15Z
dc.date.issued2022
dc.description© 2022 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)pt_PT
dc.description.abstractObjective: This study aimed to assess whether atrial fibrillation (AF) occurrence or its corresponding daily mean burden (in minutes/day) during the mid to late blanking period after pulmonary vein isolation (PVI), predicts AF recurrence. Methods: Analysis of consecutive first PVI ablation patients undergoing prolonged electrocardiogram (ECG) monitoring during the second and third months after PVI. The clinical variables, total AF burden, and their relationship with time to recurrence were studied. Results: 477 patients with a mean age of 56.9 (SD = 12.3) years (63.7 % male; 71.7 % paroxysmal AF), from which 317 (66.5 %) had an external event recorder between 30 and 90 days after ablation. Median follow-up of 16.0 (P 25:12.0: P 75:33.0) months, 177 (37 %) patients had an AF recurrence, with 106 (22.2 %) having the first episode after 12 months of follow-up. In the group of patients with an event recorder, 80 (25.2 %) had AF documented during the blanking period. Multivariable analysis showed that AF during the blanking period was associated with a 4-fold higher risk of recurrence (HR: 3.98; 95 %CI: 2.95-5.37), and, compared to patients in sinus rhythm, those with an AF burden ≥ 23 min/day had an approximately 7-fold higher risk of recurrence (HR estimate: 6.79; 95 %CI: 4.56-10.10). Conclusions: The probability of experiencing AF recurrence can be predicted by atrial tachyarrhythmia episodes during the second and third months after PVI. Atrial arrhythmias burden > 23 min/day has a high predictive ability for recurrence.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationInt J Cardiol Heart Vasc. 2022 Oct 14;43:101138pt_PT
dc.identifier.doi10.1016/j.ijcha.2022.101138pt_PT
dc.identifier.issn2352-9067
dc.identifier.urihttp://hdl.handle.net/10451/54921
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/journal/ijc-heart-and-vasculaturept_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectArrhythmia burdenpt_PT
dc.subjectArrhythmia recurrencept_PT
dc.subjectAtrial fibrillationpt_PT
dc.subjectBlanking periodpt_PT
dc.subjectCatheter ablationpt_PT
dc.subjectPulmonary vein isolationpt_PT
dc.titleThe atrial fibrillation burden during the blanking period is predictive of time to recurrence after catheter ablationpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleIJC Heart & Vasculaturept_PT
oaire.citation.volume43pt_PT
person.familyNameSilva Cunha
person.familyNameMartins Oliveira
person.givenNamePedro Miguel
person.givenNameMario Joao
person.identifier.ciencia-id4716-747F-D64E
person.identifier.ciencia-id2312-2190-19B2
person.identifier.orcid0000-0001-9465-634X
person.identifier.orcid0000-0002-8371-8354
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication77292f94-3ad4-4657-bba0-c54ab9dd641a
relation.isAuthorOfPublication81e0b444-8832-47a8-a911-2f89eb33545d
relation.isAuthorOfPublication.latestForDiscovery77292f94-3ad4-4657-bba0-c54ab9dd641a

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