A carregar...
Publicação
Padrão nutricional de doentes cirróticos e de doentes com carcinoma hepatocelular
| Nome: | Descrição: | Tamanho: | Formato: | |
|---|---|---|---|---|
| 1.39 MB | Adobe PDF |
Orientador(es)
Resumo(s)
Introdução: A cirrose, de qualquer etiologia, é reconhecida como o principal fator de risco para o desenvolvimento de carcinoma hepatocelular (CHC). Contudo, informações recentes têm vindo a sugerir que determinados estilos de vida e/ou padrões alimentares poderão ter algum impacto na sua prevenção e prognóstico.
Objetivos: Avaliar e comparar o consumo alimentar de doentes cirróticos com e sem carcinoma hepatocelular, por forma a averiguar a existência de diferenças significativas entre o padrão alimentar dos grupos em estudo, procurando determinar se existe uma relação entre os hábitos de consumo alimentar e os estadios de cirrose e carcinoma hepatocelular.
Materiais e Métodos: As informações foram recolhidas utilizando uma Tabela de registo e um Questionário de Frequência Alimentar, sendo os dados posteriormente analisados recorrendo ao software IBM SPSS Statistics.
Resultados: No total foram avaliados 39 indivíduos, divididos em 2 grupos, com 21 cirróticos sem CHC e 18 com carcinoma hepatocelular. Verificou-se que 29 doentes são do género masculino e 10 do género feminino, com uma média de idades de 64 anos, e que a principal etiologia da doença hepática é o álcool, seguida pela hepatite C. Relativamente ao padrão alimentar observaram-se apenas diferenças significativas no consumo de vitamina C e frutas, com os doentes com CHC a consumir quantidades significativamente inferiores aos doentes cirróticos sem carcinoma.
Conclusões: Nesta amostra, apesar da dimensão reduzida, verificamos que num grupo de cirróticos, os doentes que desenvolveram CHC têm menor ingestão de Vitamina C e Frutas.
Introduction: Cirrhosis of any etiology is recognized as the major risk factor for the development of hepatocellular carcinoma (HCC). However, recent data have suggested that lifestyle and eating patterns may have an impact on prevention and prognosis. Objectives: To compare the food intake of cirrhotic patients with and without HCC, in order to evaluate if there were significant differences between the dietary patterns of the studied groups, seeking to determine whether there is a relationship between food habits and the presence of HCC. Materials and Methods: The information was assembled using a Registration table and a Food Frequency Questionnaire, with the data being analyzed by the IBM SPSS Statistics software. Results: In total 39 subjects were evaluated, divided into 2 groups, with 21 cirrhotic without evidence of HCC and 18 with HCC. It was found that 29 patients were male and 10 were female, with a mean age of 64 years, and that the main cause of liver disease is alcohol, followed by chronic hepatitis C. Regarding the dietary patterns, there were only observed significant differences in the consumption of vitamin C and fruits, with patients with hepatocellular carcinoma eating significantly lower amounts than cirrhotic patients. Conclusions: In this sample, despite the small size, we found that in a cirrhotic group, the patients who presented with HCC have a lower intake of Vitamin C and Fruits.
Introduction: Cirrhosis of any etiology is recognized as the major risk factor for the development of hepatocellular carcinoma (HCC). However, recent data have suggested that lifestyle and eating patterns may have an impact on prevention and prognosis. Objectives: To compare the food intake of cirrhotic patients with and without HCC, in order to evaluate if there were significant differences between the dietary patterns of the studied groups, seeking to determine whether there is a relationship between food habits and the presence of HCC. Materials and Methods: The information was assembled using a Registration table and a Food Frequency Questionnaire, with the data being analyzed by the IBM SPSS Statistics software. Results: In total 39 subjects were evaluated, divided into 2 groups, with 21 cirrhotic without evidence of HCC and 18 with HCC. It was found that 29 patients were male and 10 were female, with a mean age of 64 years, and that the main cause of liver disease is alcohol, followed by chronic hepatitis C. Regarding the dietary patterns, there were only observed significant differences in the consumption of vitamin C and fruits, with patients with hepatocellular carcinoma eating significantly lower amounts than cirrhotic patients. Conclusions: In this sample, despite the small size, we found that in a cirrhotic group, the patients who presented with HCC have a lower intake of Vitamin C and Fruits.
Descrição
Tese de mestrado, Nutrição Clínica, Universidade de Lisboa, Faculdade de Medicina, 2016
Palavras-chave
Cirrose Carcinoma hepatocelular Padrão nutricional Teses de mestrado - 2016