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Impacto na qualidade de vida oral e sistémica da síndrome de Sjögren primária
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Objetivo: Analisar a existência de correlação entre os scores de questionários de qualidade de vida oral e sistémica (OHIP-14 e SF-12, respectivamente), os fluxos salivares e o índice de CPO numa amostra da população portuguesa com Síndrome de Sjögren Primária. Desenho do Estudo: Estudo transversal piloto. Materiais e Métodos: Amostra constituída por 30 pacientes, do Instituto Português de Reumatologia de Lisboa, com Síndrome de Sjögren Primária. Para todos os pacientes foram obtidos, previamente, os valores de fluxos salivares e índice de CPO. Posteriormente, foram realizadas duas administrações dos questionários de qualidade de vida oral e sistémica (OHIP-14 e SF-12, respectivamente). Foram analisadas a fiabilidade do teste e re-teste com o coeficiente de correlação intraclasse (ICC), a consistência interna com o coeficiente Cronbach’s alpha e eventuais correlações entre os scores totais dos questionários, fluxos salivares e índice de CPO através da correlação de Pearson. O nível de significância definido foi 0,05. Os resultados foram apresentados como média e ± 95% intervalo de confiança. Resultados: Foram obtidos bons resultados de consistência interna e de fiabilidade do teste e re-teste (OHIP-14 Cronbach’s alpha = 0,882, SF-12 Cronbach’s alpha = 0,854; OHIP-14 variação de ICC = 0,784-0,987, SF-12 variação de ICC = 0,603-0,956). A correlação de Pearson sugere a existência de uma correlação forte, negativa e significativa entre o score total do OHIP-14 e os scores total, do domínio físico e do domínio mental do SF-12 (P<0,05). Não aparenta existir correlação entre os scores dos questionários e os fluxos salivares ou índice de CPO (P>0,05). Conclusão: Existe sugestão de uma correlação entre a qualidade de vida oral e a qualidade de vida sistémica em pacientes com Síndrome de Sjögren Primária. Como tal, a sintomatologia oral e sistémica produzem uma associação de efeitos que afeta a qualidade de vida.
Objective: To analyze the possible correlation between the scores of an oral and systemic quality of life questionnaires (OHIP-14 and SF-12, respectively), the salivary flow rates and the DMF index in a sample of portuguese population with Primary Sjögren’s Syndrome Study Design: Transversal pilot study Materials and Methods: Sample of 30 patients of the Portuguese Rheumatology Institute of Lisbon with Primary Sjögren’s Syndrome. All patients salivary flow rates and DMF index were obtain previously. Afterwards, the oral and systemic quality of life questionnaires (OHIP-14 and SF-12, respectively) were administered twice. Properties were examined including test-retest reliability using intra-class correlation coefficient (ICC), internal consistency using Cronbach’s alpha and the possible correlations between the total scores of the questionnaires, the salivary flow rates and the DMF index by Pearson’s correlation. The significance level was set at 0.05. Results were presented as mean and ± 95% confidence interval. Results: Good results were obtained for internal consistency and test-retest reliability (OHIP-14 Cronbach’s alpha = 0.882, SF-12 Cronbach’s alpha = 0.854; OHIP-14 ICC range = 0.784-0.987, SF-12 ICC range = 0.603-0.956). Pearson’s correlation suggests the presence of a strong, negative and significant correlation between the OHIP-14’s total score and the SF-12’s total, physical and mental scores (P<0.05). The presence of a correlation between the questionnaires scores and the salivary flow rates or DMF index isn’t suggested (P>0,05). Conclusion: A correlation between oral and systemic quality of life is suggested in patients with Primary Sjögren’s Syndrome. As such, the oral and systemic symptoms association affects the quality of life.
Objective: To analyze the possible correlation between the scores of an oral and systemic quality of life questionnaires (OHIP-14 and SF-12, respectively), the salivary flow rates and the DMF index in a sample of portuguese population with Primary Sjögren’s Syndrome Study Design: Transversal pilot study Materials and Methods: Sample of 30 patients of the Portuguese Rheumatology Institute of Lisbon with Primary Sjögren’s Syndrome. All patients salivary flow rates and DMF index were obtain previously. Afterwards, the oral and systemic quality of life questionnaires (OHIP-14 and SF-12, respectively) were administered twice. Properties were examined including test-retest reliability using intra-class correlation coefficient (ICC), internal consistency using Cronbach’s alpha and the possible correlations between the total scores of the questionnaires, the salivary flow rates and the DMF index by Pearson’s correlation. The significance level was set at 0.05. Results were presented as mean and ± 95% confidence interval. Results: Good results were obtained for internal consistency and test-retest reliability (OHIP-14 Cronbach’s alpha = 0.882, SF-12 Cronbach’s alpha = 0.854; OHIP-14 ICC range = 0.784-0.987, SF-12 ICC range = 0.603-0.956). Pearson’s correlation suggests the presence of a strong, negative and significant correlation between the OHIP-14’s total score and the SF-12’s total, physical and mental scores (P<0.05). The presence of a correlation between the questionnaires scores and the salivary flow rates or DMF index isn’t suggested (P>0,05). Conclusion: A correlation between oral and systemic quality of life is suggested in patients with Primary Sjögren’s Syndrome. As such, the oral and systemic symptoms association affects the quality of life.
Descrição
Tese de mestrado, Medicina Dentária, Universidade de Lisboa, Faculdade de Medicina Dentária, 2014
Palavras-chave
Sídrome de Sjögren Teses de mestrado - 2014