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Bone remodeling markers and bone metastases: from cancer research to clinical implications

dc.contributor.authorFerreira, Arlindo
dc.contributor.authorAlho, Irina
dc.contributor.authorCasimiro, Sandra
dc.contributor.authorCosta, Luis
dc.date.accessioned2021-07-26T15:16:47Z
dc.date.available2021-07-26T15:16:47Z
dc.date.issued2015
dc.description© 2015 International Bone & Mineral Society All rights reserved.pt_PT
dc.description.abstractBone metastasis is a frequent finding in the natural history of several types of cancers. However, its anticipated risk, diagnosis and response to therapy are still challenging to assess in clinical practice. Markers of bone metabolism are biochemical by-products that provide insight into the tumor-bone interaction, with potential to enhance the clinical management of patients with bone metastases. In fact, these markers had a cornerstone role in the development of bone-targeted agents; however, its translation to routine practice is still unclear, as reflected by current international guidelines. In this review, we aimed to capture several of the research and clinical translational challenges regarding the use of bone metabolism markers that we consider relevant for future research in bone metastasis.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBonekey Rep. 2015 Apr 22;4:668pt_PT
dc.identifier.doi10.1038/bonekey.2015.35pt_PT
dc.identifier.eissn2047-6396
dc.identifier.urihttp://hdl.handle.net/10451/49129
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherInternational Bone & Mineral Societypt_PT
dc.relation.publisherversionhttps://www.ncbi.nlm.nih.gov/pmc/journals/2081/pt_PT
dc.relation.publisherversionhttps://www.ibmsonline.org/p/cm/ld/fid=1pt_PT
dc.titleBone remodeling markers and bone metastases: from cancer research to clinical implicationspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleBoneKEy Reportspt_PT
oaire.citation.volume4pt_PT
person.familyNameFerreira
person.familyNameCara de Anjo Casimiro
person.familyNameCosta
person.givenNameArlindo
person.givenNameSandra Cristina
person.givenNameLuis
person.identifier.ciencia-idF112-254C-6DC4
person.identifier.ciencia-id0F12-5181-0B22
person.identifier.ciencia-id041E-4ADE-FB64
person.identifier.orcid0000-0002-1567-9322
person.identifier.orcid0000-0002-6917-4477
person.identifier.orcid0000-0002-4782-7318
person.identifier.scopus-author-id56707990400
person.identifier.scopus-author-id14043403400
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication9192e5a3-8f47-42b4-9192-abd1484d32f1
relation.isAuthorOfPublicationfd665de1-a7e6-4638-94c3-ecc645f84607
relation.isAuthorOfPublication8a2ab4c6-ba86-4433-b4b7-6256d81890e5
relation.isAuthorOfPublication.latestForDiscovery9192e5a3-8f47-42b4-9192-abd1484d32f1

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