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Genetic portrait of Lisboa immigrant population from Angola with mitochondrial DNA

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dc.contributor.authorSimão, Filipa
dc.contributor.authorAfonso Costa, Heloísa
dc.contributor.authorda Silva, Claúdia Vieira
dc.contributor.authorRibeiro, Teresa
dc.contributor.authorPorto, Maria João
dc.contributor.authorSantos, Jorge Costa
dc.contributor.authorAmorim, António
dc.date.accessioned2022-05-27T16:12:21Z
dc.date.available2022-05-27T16:12:21Z
dc.date.issued2015
dc.description© 2014 Elsevier Ireland Ltd. All rights reserved.pt_PT
dc.description.abstractPortugal has been considered a country of emigrants, nevertheless in the past decades the number of immigrants has grown throughout all the country. This migratory flux has contributed to a raise of heterogeneity at multiple levels. According to statistical data, at the end of 2012 the total number of Angolan immigrants in Portugal equalled about 20,000 individuals. A territorial predominance has been found for the metropolitan region of Lisboa. Angola is a country located in the Atlantic coast of Africa. The presence of Bantu people and the colonisation by Portuguese people on Angolan territory are considered to be the major modulators of the genetic patterns in Angola. Mitochondrial DNA is known for its features that enable an approach to the study of human origin and evolution, as well to the different migration pathways of populations. This genetic marker can also contribute to ascertaining the identity of individuals in forensic cases. The main aim of this study was to determine the genetic structure of the Angolan immigrant population living in Lisboa. Therefore, a total of 173 individuals, inhabitants in Lisboa, nonrelated and with Angolan ancestry were studied. Total control region of mitochondrial DNA was amplified from position 16,024 to position 576 using two pairs of primers - L15997/H016 and L16555/H639. The majority of the identified haplotypes belong to mtDNA lineages known to be specific of the sub-Saharan region. Our results show that this immigrant population inhabitant in Lisboa presents a genetic profile that is characteristic of African populations. This study also demonstrates the genetic diversity that this immigrant population introduces in Lisboa. This does not contradict the historical data concerning colonization of Angola, since this was made mainly by male European individuals, who did not contribute with their maternal information of mtDNA. Lisboa immigrant population from Angola can be accessed via EMPOP dataset with accession number EMPOP662.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationForensic Sci Int Genet . 2015 Mar;15:33-38pt_PT
dc.identifier.doi10.1016/j.fsigen.2014.09.013pt_PT
dc.identifier.eissn1878-0326
dc.identifier.issn1872-4973
dc.identifier.urihttp://hdl.handle.net/10451/53213
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/journal/forensic-science-international-geneticspt_PT
dc.subjectAngolapt_PT
dc.subjectControl regionpt_PT
dc.subjectLisboapt_PT
dc.subjectMitochondrial DNApt_PT
dc.titleGenetic portrait of Lisboa immigrant population from Angola with mitochondrial DNApt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage38pt_PT
oaire.citation.startPage33pt_PT
oaire.citation.titleForensic Science International: Geneticspt_PT
oaire.citation.volume15pt_PT
person.familyNameAfonso Costa
person.familyNameSantos
person.familyNameAmorim
person.givenNameHeloísa
person.givenNameJorge
person.givenNameAntónio
person.identifier.orcid0000-0002-7823-7687
person.identifier.orcid0000-0002-8925-3068
person.identifier.orcid0000-0002-7506-4426
person.identifier.ridJ-5725-2015
person.identifier.ridA-4414-2013
person.identifier.scopus-author-id24729171700
person.identifier.scopus-author-id7402389332
person.identifier.scopus-author-id35253426400
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication1fe706c7-91e6-489a-80b7-95b87e61e7bf
relation.isAuthorOfPublicationdf0170ce-6eac-4fc2-80a4-e5b60ebec233
relation.isAuthorOfPublication880aab3b-98a0-4f2d-9e95-84673e09ba50
relation.isAuthorOfPublication.latestForDiscoverydf0170ce-6eac-4fc2-80a4-e5b60ebec233

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