Exploring the phytochemicals of Acacia melanoxylon R. Br.

Alves, Diana; Duarte, Sidónio; Arsénio, Pedro; Gonçalves, Joana; Rodrigues, Cecíla M.P.; Ana Lourenço, Lourenço; Patrícia Máximo

http://hdl.handle.net/10400.5/22757

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Autores

Rodrigues, Cecíla M.P.

Ana Lourenço, Lourenço

Patrícia Máximo

Resumo(s)

Invasive species are currently a world menace to the environment, although the study of their chemistry may provide a means for their future beneficial use. From a study of Portuguese Acacia melanoxylon R. Br. five known compounds were isolated: lupeol, 3 -Z-coumaroyl lupeol, 3 -E-coumaroyl lupeol (dioslupecin A), kolavic acid 15-methyl ester and vomifoliol (blumenol A). Their structures were elucidated by 1D and 2D NMR spectroscopy and mass spectrometry, and as a result some corrections are made to their previous 13C NMR assignments. Cytotoxicity of 3 -Ecoumaroyl lupeol (dioslupecin A) and kolavic acid 15-methyl ester was evaluated against HCT116 human colorectal cancer cells although biological activity was not evident

Palavras-chave

invasive species Acacia melanoxylon terpenoids HCT116 human colorectal cancer cells cytotoxicity

URI

http://hdl.handle.net/10400.5/22757

Citação

Alves, D.; Duarte, S.; Arsénio, P.; Gonçalves, J.; Rodrigues, C.M.P.; Lourenço, A.; Máximo, P. Exploring the Phytochemicals of Acacia melanoxylon R. Br. Plants 2021